Abstract
In the contemporary era of potent immunosuppressive regimens, previously encountered signs of renal allograft rejection such as fever and hematuria are rarely encountered. We report a teenager with severe recurrent acute humoral and cellular rejection whose presenting feature was gross hematuria with the presence of blood clots in the urine. We want to highlight that severe rejection even in the setting of modern immunosuppressive drugs can present as gross hematuria. Contrary to conventional wisdom that gross hematuria with the presence of blood clots in the urine is indicative of pathology in the renal collecting system, a parenchymal disease process should also be considered in renal transplant recipients.
| Original language | English (US) |
|---|---|
| Journal | Pediatric Transplantation |
| Volume | 18 |
| Issue number | 4 |
| DOIs | |
| State | Published - 2014 |
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Keywords
- hematuria
- kidney transplantation
- rejection
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Transplantation
- Medicine(all)
Cite this
Gross hematuria as a sign of acute rejection. / Winnicki, Erica; Nguyen, Stephanie; Butani, Lavjay.
In: Pediatric Transplantation, Vol. 18, No. 4, 2014.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Gross hematuria as a sign of acute rejection
AU - Winnicki, Erica
AU - Nguyen, Stephanie
AU - Butani, Lavjay
PY - 2014
Y1 - 2014
N2 - In the contemporary era of potent immunosuppressive regimens, previously encountered signs of renal allograft rejection such as fever and hematuria are rarely encountered. We report a teenager with severe recurrent acute humoral and cellular rejection whose presenting feature was gross hematuria with the presence of blood clots in the urine. We want to highlight that severe rejection even in the setting of modern immunosuppressive drugs can present as gross hematuria. Contrary to conventional wisdom that gross hematuria with the presence of blood clots in the urine is indicative of pathology in the renal collecting system, a parenchymal disease process should also be considered in renal transplant recipients.
AB - In the contemporary era of potent immunosuppressive regimens, previously encountered signs of renal allograft rejection such as fever and hematuria are rarely encountered. We report a teenager with severe recurrent acute humoral and cellular rejection whose presenting feature was gross hematuria with the presence of blood clots in the urine. We want to highlight that severe rejection even in the setting of modern immunosuppressive drugs can present as gross hematuria. Contrary to conventional wisdom that gross hematuria with the presence of blood clots in the urine is indicative of pathology in the renal collecting system, a parenchymal disease process should also be considered in renal transplant recipients.
KW - hematuria
KW - kidney transplantation
KW - rejection
UR - http://www.scopus.com/inward/record.url?scp=84900014195&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84900014195&partnerID=8YFLogxK
U2 - 10.1111/petr.12258
DO - 10.1111/petr.12258
M3 - Article
C2 - 24802349
AN - SCOPUS:84900014195
VL - 18
JO - Pediatric Transplantation
JF - Pediatric Transplantation
SN - 1397-3142
IS - 4
ER -