Grey matter abnormality in progressive multifocal leucoencephalopathy

Christopher Yuki Itoh, Han Sung Lee, Alan Howe Yee

Research output: Contribution to journalArticlepeer-review


Progressive multifocal leucoencephalopathy (PML) is a demyelinating white matter disease that most often affects immunocompromised people infected by JC virus. The diagnostic gold standard is demonstrable viral DNA or protein from histopathological tissue. However, there are few detailed descriptions of cortical grey matter involvement on neuroimaging. Here we describe the histopathological correlate of cerebral grey matter involvement and radiological accompaniment in a patient with biopsy proven PML.

Original languageEnglish (US)
JournalPractical Neurology
StateAccepted/In press - 2021


  • CSF
  • infectious diseases
  • neuropathology
  • neuroradiology
  • virology

ASJC Scopus subject areas

  • Clinical Neurology


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