Green tea and breast cancer

Anna H. Wu, Lesley M. Butler

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The identification of modifiable lifestyle factors that could reduce the risk of breast cancer is a research priority. Despite the enormous chemopreventive potential of green tea and compelling evidence from animal studies, its role in breast cancer development in humans is still unclear. Part of the uncertainty is related to the relatively small number of epidemiological studies on green tea and breast cancer and that the overall results from case-control studies and prospective cohort studies are discordant. In addition, the mechanisms by which green tea intake may influence risk of breast cancer in humans remain not well studied. We review the human studies that have evaluated the relationship between green tea intake and four biomarkers (sex steroid hormones, mammographic density, insulin-like growth factor, adiponectin) that are believed to be important in breast cancer development. Results from these biomarker studies are also inconclusive. Limitations of observational studies and areas of further investigations are discussed.

Original languageEnglish (US)
Pages (from-to)921-930
Number of pages10
JournalMolecular Nutrition and Food Research
Volume55
Issue number6
DOIs
StatePublished - Jun 2011
Externally publishedYes

Fingerprint

green tea
Tea
breast neoplasms
Breast Neoplasms
biomarkers
Biomarkers
adiponectin
human development
sex hormones
Adiponectin
somatomedins
Gonadal Steroid Hormones
Human Development
steroid hormones
Somatomedins
observational studies
case-control studies
cohort studies
epidemiological studies
Uncertainty

Keywords

  • Breast cancer
  • Circulating hormone levels
  • Green tea
  • Insulin-like growth factor
  • Mammographic density

ASJC Scopus subject areas

  • Food Science
  • Biotechnology

Cite this

Green tea and breast cancer. / Wu, Anna H.; Butler, Lesley M.

In: Molecular Nutrition and Food Research, Vol. 55, No. 6, 06.2011, p. 921-930.

Research output: Contribution to journalArticle

Wu, Anna H. ; Butler, Lesley M. / Green tea and breast cancer. In: Molecular Nutrition and Food Research. 2011 ; Vol. 55, No. 6. pp. 921-930.
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