Une production laitiére accrue est reliée ádes concentrations supérieures d'ADN et d'ARN mais pas à l'abondance de l'ARNm de génes cibles dans les glandes mammaires de truies

Translated title of the contribution: Greater milk yield is related to increased DNA and RNA content but not to mRNA abundance of selected genes in sow mammary tissue

C. Farmer, M. F. Palin, R. C. Hovey

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The relationship between greater sow milk yield and mammary development, expression of selected genes in mammary tissue and hormonal concentrations in lactating sows was studied. Crossbred sows were separated in two groups according to the weight gains of their piglets up to day 21. The groups were: (1) lower milk yield (LOW, n=14) and (2) higher milk yield (HI, n=14), representing lactation weight gains of 4.46 and 5.25 kg pig-1, respectively. Jugular blood samples were obtained from all sows on day 3 (for prolactin determination) and day 23 (for measures of prolactin, leptin, insulin, glucose and free fatty acids) of lactation, and milk samples were collected on days 3 and 22. At weaning (day 23), sows were slaughtered and their mammary glands were collected, dissected and composition was determined. Mammary parenchymal tissue was analyzed for the mRNA abundance of selected genes. Hormone concentrations in blood did not differ between groups (P>0.1) and on day 3 of lactation, dry matter and leptin contents in milk were lower (P<0.05) in HI than in LOW sows. There was more DNA and RNA per teat in HI than LOW sows (P<0.05), whereas the expression of selected genes within mammary tissue was unaffected (P>0.1) by production group. Significant correlations (P<0.01) existed between average weight gain of piglets during lactation and mammary RNA and DNA, expressed either as total amount or amount per teat, at weaning. Sow milk yield is therefore related to mammary gland composition in late lactation.

Original languageFrench
Pages (from-to)379-388
Number of pages10
JournalCanadian Journal of Animal Science
Volume90
Issue number3
DOIs
StatePublished - 2010

Fingerprint

breasts
sows
milk yield
Milk
Lactation
Breast
lactation
RNA
sow milk
Messenger RNA
DNA
weight gain
prolactin
leptin
mammary glands
Genes
Weight Gain
piglets
weaning
genes

Keywords

  • Genes
  • Lactation
  • Mammary gland
  • Milk yield
  • Sow

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Food Animals

Cite this

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title = "Une production laiti{\'e}re accrue est reli{\'e}e {\'a}des concentrations sup{\'e}rieures d'ADN et d'ARN mais pas {\`a} l'abondance de l'ARNm de g{\'e}nes cibles dans les glandes mammaires de truies",
abstract = "The relationship between greater sow milk yield and mammary development, expression of selected genes in mammary tissue and hormonal concentrations in lactating sows was studied. Crossbred sows were separated in two groups according to the weight gains of their piglets up to day 21. The groups were: (1) lower milk yield (LOW, n=14) and (2) higher milk yield (HI, n=14), representing lactation weight gains of 4.46 and 5.25 kg pig-1, respectively. Jugular blood samples were obtained from all sows on day 3 (for prolactin determination) and day 23 (for measures of prolactin, leptin, insulin, glucose and free fatty acids) of lactation, and milk samples were collected on days 3 and 22. At weaning (day 23), sows were slaughtered and their mammary glands were collected, dissected and composition was determined. Mammary parenchymal tissue was analyzed for the mRNA abundance of selected genes. Hormone concentrations in blood did not differ between groups (P>0.1) and on day 3 of lactation, dry matter and leptin contents in milk were lower (P<0.05) in HI than in LOW sows. There was more DNA and RNA per teat in HI than LOW sows (P<0.05), whereas the expression of selected genes within mammary tissue was unaffected (P>0.1) by production group. Significant correlations (P<0.01) existed between average weight gain of piglets during lactation and mammary RNA and DNA, expressed either as total amount or amount per teat, at weaning. Sow milk yield is therefore related to mammary gland composition in late lactation.",
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author = "C. Farmer and Palin, {M. F.} and Hovey, {R. C.}",
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AU - Hovey, R. C.

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AB - The relationship between greater sow milk yield and mammary development, expression of selected genes in mammary tissue and hormonal concentrations in lactating sows was studied. Crossbred sows were separated in two groups according to the weight gains of their piglets up to day 21. The groups were: (1) lower milk yield (LOW, n=14) and (2) higher milk yield (HI, n=14), representing lactation weight gains of 4.46 and 5.25 kg pig-1, respectively. Jugular blood samples were obtained from all sows on day 3 (for prolactin determination) and day 23 (for measures of prolactin, leptin, insulin, glucose and free fatty acids) of lactation, and milk samples were collected on days 3 and 22. At weaning (day 23), sows were slaughtered and their mammary glands were collected, dissected and composition was determined. Mammary parenchymal tissue was analyzed for the mRNA abundance of selected genes. Hormone concentrations in blood did not differ between groups (P>0.1) and on day 3 of lactation, dry matter and leptin contents in milk were lower (P<0.05) in HI than in LOW sows. There was more DNA and RNA per teat in HI than LOW sows (P<0.05), whereas the expression of selected genes within mammary tissue was unaffected (P>0.1) by production group. Significant correlations (P<0.01) existed between average weight gain of piglets during lactation and mammary RNA and DNA, expressed either as total amount or amount per teat, at weaning. Sow milk yield is therefore related to mammary gland composition in late lactation.

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