Granulosa Cell Tumors in two cycling mares

P. M. McCue,, M. M. LeBlanc,, G. Y. Akita,, John Pascoe, D. M. Witherspoon,, G. H. Stabenfeldt,

Research output: Contribution to journalArticle

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Abstract

The granulosa-theca cell tumor (GTCT) is the most common ovarian tumor of the horse.4,7 Mares with a GTCT may exhibit continuous or intermittent estrus, stallion-like behavior or may remain anestrus.4 The hormone secretory profile of the tumor dictates the behavior expressed, with mares having elevated plasma testosterone concentrations (>100 pg/ml) exhibiting stallion-like behavior.7 The ultrasonic appearance of the affected ovary ranges from a homogenous echogenic mass to a multicystic or 'honeycomb' pattern.1 The contralateral ovary is usually small and inactive,4,7 although one mare with a functional contralateral ovary was recently described.2 Mares with an inactive contralateral ovary resume normal cyclic ovarian activity 2-16 months after removal of the affected ovary4 Clinical diagnosis of a GTCT is based on history, behavior, presence of a unilaterally enlarged ovary with an inactive contralateral ovary, and in some cases, elevated plasma testosterone concentrations. This report documents the presence of a granulosa cell tumor in two mares which exhibited normal follicular development, ovulation and luteal function in the contralateral ovary.

Original languageEnglish (US)
Pages (from-to)281-282
Number of pages2
JournalJournal of Equine Veterinary Science
Volume11
Issue number5
DOIs
StatePublished - Jan 1 1991

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Granulosa Cell Tumor
granulosa cells
mares
Ovary
neoplasms
stallions
testosterone
Testosterone
combs (social insects)
ovarian neoplasms
follicular development
corpus luteum
ovulation
estrus
ultrasonics
Corpus Luteum
Estrus
hormones
Ovulation
Ultrasonics

ASJC Scopus subject areas

  • Equine

Cite this

McCue, P. M., LeBlanc, M. M., Akita, G. Y., Pascoe, J., Witherspoon, D. M., & Stabenfeldt, G. H. (1991). Granulosa Cell Tumors in two cycling mares. Journal of Equine Veterinary Science, 11(5), 281-282. https://doi.org/10.1016/S0737-0806(06)81316-X

Granulosa Cell Tumors in two cycling mares. / McCue, P. M.; LeBlanc, M. M.; Akita, G. Y.; Pascoe, John; Witherspoon, D. M.; Stabenfeldt, G. H.

In: Journal of Equine Veterinary Science, Vol. 11, No. 5, 01.01.1991, p. 281-282.

Research output: Contribution to journalArticle

McCue, PM, LeBlanc, MM, Akita, GY, Pascoe, J, Witherspoon, DM & Stabenfeldt, GH 1991, 'Granulosa Cell Tumors in two cycling mares', Journal of Equine Veterinary Science, vol. 11, no. 5, pp. 281-282. https://doi.org/10.1016/S0737-0806(06)81316-X
McCue, PM, LeBlanc, MM, Akita, GY, Pascoe J, Witherspoon, DM, Stabenfeldt, GH. Granulosa Cell Tumors in two cycling mares. Journal of Equine Veterinary Science. 1991 Jan 1;11(5):281-282. https://doi.org/10.1016/S0737-0806(06)81316-X
McCue, P. M. ; LeBlanc, M. M. ; Akita, G. Y. ; Pascoe, John ; Witherspoon, D. M. ; Stabenfeldt, G. H. / Granulosa Cell Tumors in two cycling mares. In: Journal of Equine Veterinary Science. 1991 ; Vol. 11, No. 5. pp. 281-282.
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