Granulocytic ehrlichiosis in two dogs in Switzerland

Nicola Pusterla, Jon Huder, Celestine Wolfensberger, Bruno Litschi, Anne Parvis, Hans Lutz

Research output: Contribution to journalArticlepeer-review

64 Scopus citations


This case report describes two dogs with granulocytic ehrlichiosis. Dog 1 was a male Labrador retriever with clinical signs of lymphosarcoma. Dog 2 was a female Airedale terrier, whose clinical signs included apathy, pyrexia, diarrhea, and abdominal pain. Examination of blood smears revealed Ehrlichia organisms in the neutrophils of both dogs. There was thrombocytopenia in both dogs, and dog 2 also had leukopenia. In both dogs, bands of identical length were amplified from DNA of leukocytes via nested PCR. The bands had identical nucleotide sequences, which differed from the gene sequences of Ehrlichia equi and E. phagocytophila in three and two positions, respectively. Interestingly, the nucleotide sequence of the 16S rRNA was 100% homologous to that of a human granulocytic ehrlichia.

Original languageEnglish (US)
Pages (from-to)2307-2309
Number of pages3
JournalJournal of Clinical Microbiology
Issue number9
StatePublished - Sep 1997
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology


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