Gold-coated iron nanoparticles: A novel magnetic resonance agent for T 1 and T2 weighted imaging

Sung Jin Cho; Benjamin R. Jarrett; Angelique Y. Louie; Susan M. Kauzlarich

doi:10.1088/0957-4484/17/3/004

Gold-coated iron nanoparticles: A novel magnetic resonance agent for T ₁ and T₂ weighted imaging

Sung Jin Cho, Benjamin R. Jarrett, Angelique Y. Louie, Susan M. Kauzlarich

Research output: Contribution to journal › Article › peer-review

114 Scopus citations

Abstract

Core/shell structured iron(Fe)/gold(Au) nanoparticles have been prepared by a reverse micelle method, and their potential application as magnetic resonance (MR) contrast agent investigated. The average nanoparticle size is 19 nm, as determined by x-ray powder diffraction (XRD) and transmission electron microscopy (TEM). Magnetic properties and relaxivities of nanoparticles are presented and compared. The saturation magnetization is 81 emu g^-1 Fe for freshly prepared nanoparticles and the particles have high r ₁(6.87 mM^-1 s^-1) when the Fe core is kept from oxidation. These nanoparticles may be used as T₁ agents in the unoxidized form.

Original language	English (US)
Pages (from-to)	640-644
Number of pages	5
Journal	Nanotechnology
Volume	17
Issue number	3
DOIs	https://doi.org/10.1088/0957-4484/17/3/004
State	Published - Feb 14 2006

ASJC Scopus subject areas

Engineering (miscellaneous)
Materials Science(all)
Physics and Astronomy (miscellaneous)

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title = "Gold-coated iron nanoparticles: A novel magnetic resonance agent for T 1 and T2 weighted imaging",

abstract = "Core/shell structured iron(Fe)/gold(Au) nanoparticles have been prepared by a reverse micelle method, and their potential application as magnetic resonance (MR) contrast agent investigated. The average nanoparticle size is 19 nm, as determined by x-ray powder diffraction (XRD) and transmission electron microscopy (TEM). Magnetic properties and relaxivities of nanoparticles are presented and compared. The saturation magnetization is 81 emu g-1 Fe for freshly prepared nanoparticles and the particles have high r 1(6.87 mM-1 s-1) when the Fe core is kept from oxidation. These nanoparticles may be used as T1 agents in the unoxidized form.",

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AU - Jarrett, Benjamin R.

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AU - Kauzlarich, Susan M.

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AB - Core/shell structured iron(Fe)/gold(Au) nanoparticles have been prepared by a reverse micelle method, and their potential application as magnetic resonance (MR) contrast agent investigated. The average nanoparticle size is 19 nm, as determined by x-ray powder diffraction (XRD) and transmission electron microscopy (TEM). Magnetic properties and relaxivities of nanoparticles are presented and compared. The saturation magnetization is 81 emu g-1 Fe for freshly prepared nanoparticles and the particles have high r 1(6.87 mM-1 s-1) when the Fe core is kept from oxidation. These nanoparticles may be used as T1 agents in the unoxidized form.

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Gold-coated iron nanoparticles: A novel magnetic resonance agent for T ₁ and T₂ weighted imaging

Abstract

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