Gold-coated iron nanoparticles: A novel magnetic resonance agent for T 1 and T2 weighted imaging

Sung Jin Cho, Benjamin R. Jarrett, Angelique Y. Louie, Susan M. Kauzlarich

Research output: Contribution to journalArticle

107 Scopus citations

Abstract

Core/shell structured iron(Fe)/gold(Au) nanoparticles have been prepared by a reverse micelle method, and their potential application as magnetic resonance (MR) contrast agent investigated. The average nanoparticle size is 19 nm, as determined by x-ray powder diffraction (XRD) and transmission electron microscopy (TEM). Magnetic properties and relaxivities of nanoparticles are presented and compared. The saturation magnetization is 81 emu g-1 Fe for freshly prepared nanoparticles and the particles have high r 1(6.87 mM-1 s-1) when the Fe core is kept from oxidation. These nanoparticles may be used as T1 agents in the unoxidized form.

Original languageEnglish (US)
Pages (from-to)640-644
Number of pages5
JournalNanotechnology
Volume17
Issue number3
DOIs
StatePublished - Feb 14 2006

ASJC Scopus subject areas

  • Engineering (miscellaneous)
  • Materials Science(all)
  • Physics and Astronomy (miscellaneous)

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