Glucose dispersion measurement using white-light LCI

J. Liu; M. Bagherzadeh; C. K. Hitzenberger; M. Pircher; Robert Zawadzki; A. F. Fercher

doi:10.1117/12.478974

Glucose dispersion measurement using white-light LCI

J. Liu, M. Bagherzadeh, C. K. Hitzenberger, M. Pircher, Robert Zawadzki, A. F. Fercher

Research output: Contribution to journal › Conference article › peer-review

6 Scopus citations

Abstract

We measured second order dispersion of glucose solution using a Michelson Low Coherent Interferometer (LCI). Three different glucose concentrations: 20mg/dl (hypoglycemia), l00mg/dl (normal level), and 500mg/dl (hyperglycemia) are investigated over the wavelength range O.5μm to 0.85μm, and the investigation shows that different concentrations are associated with different second-order dispersions. The second-order dispersions for wavelengths from 0.55μm to 0.8μm are determined by Fourier analysis of the interferogram. This approach can be applied to measure the second-order dispersion for distinguishing the different glucose concentrations. It can be considered as a potentially noninvasive method to determine glucose concentration in human eye. A brief discussion is presented in this poster as well.

Original language	English (US)
Pages (from-to)	348-351
Number of pages	4
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	4956
DOIs	https://doi.org/10.1117/12.478974
State	Published - Dec 5 2003
Externally published	Yes
Event	PROGRESS IN BIOMEDICAL OPTICS AND IMAGING: Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VII - San Jose, CA, United States Duration: Jan 27 2003 → Jan 29 2003

Keywords

Coherence and statistical optics
Dispersion
Interferometry
Optical properties
Thermal light sources

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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title = "Glucose dispersion measurement using white-light LCI",

abstract = "We measured second order dispersion of glucose solution using a Michelson Low Coherent Interferometer (LCI). Three different glucose concentrations: 20mg/dl (hypoglycemia), l00mg/dl (normal level), and 500mg/dl (hyperglycemia) are investigated over the wavelength range O.5μm to 0.85μm, and the investigation shows that different concentrations are associated with different second-order dispersions. The second-order dispersions for wavelengths from 0.55μm to 0.8μm are determined by Fourier analysis of the interferogram. This approach can be applied to measure the second-order dispersion for distinguishing the different glucose concentrations. It can be considered as a potentially noninvasive method to determine glucose concentration in human eye. A brief discussion is presented in this poster as well.",

keywords = "Coherence and statistical optics, Dispersion, Interferometry, Optical properties, Thermal light sources",

author = "J. Liu and M. Bagherzadeh and Hitzenberger, {C. K.} and M. Pircher and Robert Zawadzki and Fercher, {A. F.}",

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T1 - Glucose dispersion measurement using white-light LCI

AU - Liu, J.

AU - Bagherzadeh, M.

AU - Hitzenberger, C. K.

AU - Pircher, M.

AU - Zawadzki, Robert

AU - Fercher, A. F.

PY - 2003/12/5

Y1 - 2003/12/5

N2 - We measured second order dispersion of glucose solution using a Michelson Low Coherent Interferometer (LCI). Three different glucose concentrations: 20mg/dl (hypoglycemia), l00mg/dl (normal level), and 500mg/dl (hyperglycemia) are investigated over the wavelength range O.5μm to 0.85μm, and the investigation shows that different concentrations are associated with different second-order dispersions. The second-order dispersions for wavelengths from 0.55μm to 0.8μm are determined by Fourier analysis of the interferogram. This approach can be applied to measure the second-order dispersion for distinguishing the different glucose concentrations. It can be considered as a potentially noninvasive method to determine glucose concentration in human eye. A brief discussion is presented in this poster as well.

AB - We measured second order dispersion of glucose solution using a Michelson Low Coherent Interferometer (LCI). Three different glucose concentrations: 20mg/dl (hypoglycemia), l00mg/dl (normal level), and 500mg/dl (hyperglycemia) are investigated over the wavelength range O.5μm to 0.85μm, and the investigation shows that different concentrations are associated with different second-order dispersions. The second-order dispersions for wavelengths from 0.55μm to 0.8μm are determined by Fourier analysis of the interferogram. This approach can be applied to measure the second-order dispersion for distinguishing the different glucose concentrations. It can be considered as a potentially noninvasive method to determine glucose concentration in human eye. A brief discussion is presented in this poster as well.

KW - Coherence and statistical optics

KW - Dispersion

KW - Interferometry

KW - Optical properties

KW - Thermal light sources

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