Glomerulopathy in dogs with congenital portosystemic shunts

P. L C Tisdall, T. L W Rothwell, Geraldine B Hunt, R. Malik

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Kidney specimens from 12 dogs with congenital portosystemic shunts were examined histologically. Glomerulopathy of variable severity was present in the kidney sections of all 12. Marked irregular thickening of the glomerular capillary wall was the most prominent pathological change, the renal interstitium being largely unaffected. The severity of lesions was not correlated with the age of dogs at the time of necropsy. An immunoperoxidase technique failed to demonstrate significant IgA or IgG deposition in affected glomeruli. Proteinuria was generally mild or absent despite significant glomerular lesions, except in dogs with concurrent urinary tract infection.

Original languageEnglish (US)
Pages (from-to)52-54
Number of pages3
JournalAustralian Veterinary Journal
Volume73
Issue number2
StatePublished - Feb 1996
Externally publishedYes

ASJC Scopus subject areas

  • veterinary(all)

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    Tisdall, P. L. C., Rothwell, T. L. W., Hunt, G. B., & Malik, R. (1996). Glomerulopathy in dogs with congenital portosystemic shunts. Australian Veterinary Journal, 73(2), 52-54.