Glomerular filtration response to acute ureteral obstruction in the dog

Richard W Katzberg, T. W. Morris, P. L. DiMarco, P. A. Merguerian, J. A. Ventura, C. A. Linke, H. W. Fischer

Research output: Contribution to journalArticle

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Abstract

In order to assess the glomerular filtration responses to acute ureteral obstruction in the dog we employed an established method that does not require timed urine collections. Our results show a 57 per cent increase in renal blood flow (baseline: 203.8 ± 50.9 vs. 319 ± 69.4 ml./min. at 105 minutes; no. = 7) that was associated with a monophasic decrease in filtration fraction to -70 per cent at 120 minutes (0.26 ± 0.025 vs. 0.08 ± 0.007) and an increase in ureteral pressure to 63.1 ± 6.1 mm. Hg at 120 minutes. A biphasic GFR response was noted with an initial small increase (baseline: 32.5 ± 7.5 vs. 36.3 ± 11.0 ml./min. at 2 minutes) followed by a continual decline to -55 per cent at 120 minutes (to 14.5 ± 2.6 ml./min.). This investigation has confirmed the results of micropuncture studies showing maintenance of GFR early after complete ureteral ligation.

Original languageEnglish (US)
Pages (from-to)1007-1010
Number of pages4
JournalJournal of Urology
Volume134
Issue number5
StatePublished - 1985
Externally publishedYes

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Ureteral Obstruction
Dogs
Urine Specimen Collection
Renal Circulation
Punctures
Ligation
Maintenance
Pressure

ASJC Scopus subject areas

  • Urology

Cite this

Katzberg, R. W., Morris, T. W., DiMarco, P. L., Merguerian, P. A., Ventura, J. A., Linke, C. A., & Fischer, H. W. (1985). Glomerular filtration response to acute ureteral obstruction in the dog. Journal of Urology, 134(5), 1007-1010.

Glomerular filtration response to acute ureteral obstruction in the dog. / Katzberg, Richard W; Morris, T. W.; DiMarco, P. L.; Merguerian, P. A.; Ventura, J. A.; Linke, C. A.; Fischer, H. W.

In: Journal of Urology, Vol. 134, No. 5, 1985, p. 1007-1010.

Research output: Contribution to journalArticle

Katzberg, RW, Morris, TW, DiMarco, PL, Merguerian, PA, Ventura, JA, Linke, CA & Fischer, HW 1985, 'Glomerular filtration response to acute ureteral obstruction in the dog', Journal of Urology, vol. 134, no. 5, pp. 1007-1010.
Katzberg RW, Morris TW, DiMarco PL, Merguerian PA, Ventura JA, Linke CA et al. Glomerular filtration response to acute ureteral obstruction in the dog. Journal of Urology. 1985;134(5):1007-1010.
Katzberg, Richard W ; Morris, T. W. ; DiMarco, P. L. ; Merguerian, P. A. ; Ventura, J. A. ; Linke, C. A. ; Fischer, H. W. / Glomerular filtration response to acute ureteral obstruction in the dog. In: Journal of Urology. 1985 ; Vol. 134, No. 5. pp. 1007-1010.
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AU - Linke, C. A.

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