Abstract
In order to assess the glomerular filtration responses to acute ureteral obstruction in the dog we employed an established method that does not require timed urine collections. Our results show a 57 per cent increase in renal blood flow (baseline: 203.8 ± 50.9 vs. 319 ± 69.4 ml./min. at 105 minutes; no. = 7) that was associated with a monophasic decrease in filtration fraction to -70 per cent at 120 minutes (0.26 ± 0.025 vs. 0.08 ± 0.007) and an increase in ureteral pressure to 63.1 ± 6.1 mm. Hg at 120 minutes. A biphasic GFR response was noted with an initial small increase (baseline: 32.5 ± 7.5 vs. 36.3 ± 11.0 ml./min. at 2 minutes) followed by a continual decline to -55 per cent at 120 minutes (to 14.5 ± 2.6 ml./min.). This investigation has confirmed the results of micropuncture studies showing maintenance of GFR early after complete ureteral ligation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1007-1010 |
| Number of pages | 4 |
| Journal | Journal of Urology |
| Volume | 134 |
| Issue number | 5 |
| State | Published - 1985 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Urology
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Glomerular filtration response to acute ureteral obstruction in the dog. / Katzberg, Richard W; Morris, T. W.; DiMarco, P. L.; Merguerian, P. A.; Ventura, J. A.; Linke, C. A.; Fischer, H. W.
In: Journal of Urology, Vol. 134, No. 5, 1985, p. 1007-1010.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Glomerular filtration response to acute ureteral obstruction in the dog
AU - Katzberg, Richard W
AU - Morris, T. W.
AU - DiMarco, P. L.
AU - Merguerian, P. A.
AU - Ventura, J. A.
AU - Linke, C. A.
AU - Fischer, H. W.
PY - 1985
Y1 - 1985
N2 - In order to assess the glomerular filtration responses to acute ureteral obstruction in the dog we employed an established method that does not require timed urine collections. Our results show a 57 per cent increase in renal blood flow (baseline: 203.8 ± 50.9 vs. 319 ± 69.4 ml./min. at 105 minutes; no. = 7) that was associated with a monophasic decrease in filtration fraction to -70 per cent at 120 minutes (0.26 ± 0.025 vs. 0.08 ± 0.007) and an increase in ureteral pressure to 63.1 ± 6.1 mm. Hg at 120 minutes. A biphasic GFR response was noted with an initial small increase (baseline: 32.5 ± 7.5 vs. 36.3 ± 11.0 ml./min. at 2 minutes) followed by a continual decline to -55 per cent at 120 minutes (to 14.5 ± 2.6 ml./min.). This investigation has confirmed the results of micropuncture studies showing maintenance of GFR early after complete ureteral ligation.
AB - In order to assess the glomerular filtration responses to acute ureteral obstruction in the dog we employed an established method that does not require timed urine collections. Our results show a 57 per cent increase in renal blood flow (baseline: 203.8 ± 50.9 vs. 319 ± 69.4 ml./min. at 105 minutes; no. = 7) that was associated with a monophasic decrease in filtration fraction to -70 per cent at 120 minutes (0.26 ± 0.025 vs. 0.08 ± 0.007) and an increase in ureteral pressure to 63.1 ± 6.1 mm. Hg at 120 minutes. A biphasic GFR response was noted with an initial small increase (baseline: 32.5 ± 7.5 vs. 36.3 ± 11.0 ml./min. at 2 minutes) followed by a continual decline to -55 per cent at 120 minutes (to 14.5 ± 2.6 ml./min.). This investigation has confirmed the results of micropuncture studies showing maintenance of GFR early after complete ureteral ligation.
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UR - http://www.scopus.com/inward/citedby.url?scp=0022348027&partnerID=8YFLogxK
M3 - Article
C2 - 4057362
AN - SCOPUS:0022348027
VL - 134
SP - 1007
EP - 1010
JO - Journal of Urology
JF - Journal of Urology
SN - 0022-5347
IS - 5
ER -