Giant juvenile nasopharyngeal angiofibroma

Management by skull-base surgery

Paul J. Donald, Danny Enepikedes, James E Boggan

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

From 1977 to 2001, 5 patients were seen with giant angiofibromas that had intracranial penetration. Three of these had involvement of the cavernous sinus with angiographic evidence of significant blood supply to the tumor. We attempted complete tumor removal in all patients via a skull-base procedure. The infratemporal fossa/middle fossa approach was used in 3 patients, an anterior craniofacial approach in 1, and an anterior subcranial approach in 1. Complete tumor removal was achieved in 4 patients and incomplete excision in 1. The latter was attempted with an anterior subcranial approach but required an infratemporal fossa/middle fossa approach for completion because of unanticipated cavernous sinus involvement. The patient declined further surgery. This was the only patient who had persistent disease. Preoperative and intraoperative management, blood loss, complications, and residual effects are described.

Original languageEnglish (US)
Pages (from-to)882-886
Number of pages5
JournalArchives of Otolaryngology - Head and Neck Surgery
Volume130
Issue number7
DOIs
StatePublished - Jul 2004

Fingerprint

Angiofibroma
Skull Base
Cavernous Sinus
Neoplasms

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Giant juvenile nasopharyngeal angiofibroma : Management by skull-base surgery. / Donald, Paul J.; Enepikedes, Danny; Boggan, James E.

In: Archives of Otolaryngology - Head and Neck Surgery, Vol. 130, No. 7, 07.2004, p. 882-886.

Research output: Contribution to journalArticle

@article{245a039d91c544ca83ebd4096f9042b1,
title = "Giant juvenile nasopharyngeal angiofibroma: Management by skull-base surgery",
abstract = "From 1977 to 2001, 5 patients were seen with giant angiofibromas that had intracranial penetration. Three of these had involvement of the cavernous sinus with angiographic evidence of significant blood supply to the tumor. We attempted complete tumor removal in all patients via a skull-base procedure. The infratemporal fossa/middle fossa approach was used in 3 patients, an anterior craniofacial approach in 1, and an anterior subcranial approach in 1. Complete tumor removal was achieved in 4 patients and incomplete excision in 1. The latter was attempted with an anterior subcranial approach but required an infratemporal fossa/middle fossa approach for completion because of unanticipated cavernous sinus involvement. The patient declined further surgery. This was the only patient who had persistent disease. Preoperative and intraoperative management, blood loss, complications, and residual effects are described.",
author = "Donald, {Paul J.} and Danny Enepikedes and Boggan, {James E}",
year = "2004",
month = "7",
doi = "10.1001/archotol.130.7.882",
language = "English (US)",
volume = "130",
pages = "882--886",
journal = "JAMA Otolaryngology - Head and Neck Surgery",
issn = "2168-6181",
publisher = "American Medical Association",
number = "7",

}

TY - JOUR

T1 - Giant juvenile nasopharyngeal angiofibroma

T2 - Management by skull-base surgery

AU - Donald, Paul J.

AU - Enepikedes, Danny

AU - Boggan, James E

PY - 2004/7

Y1 - 2004/7

N2 - From 1977 to 2001, 5 patients were seen with giant angiofibromas that had intracranial penetration. Three of these had involvement of the cavernous sinus with angiographic evidence of significant blood supply to the tumor. We attempted complete tumor removal in all patients via a skull-base procedure. The infratemporal fossa/middle fossa approach was used in 3 patients, an anterior craniofacial approach in 1, and an anterior subcranial approach in 1. Complete tumor removal was achieved in 4 patients and incomplete excision in 1. The latter was attempted with an anterior subcranial approach but required an infratemporal fossa/middle fossa approach for completion because of unanticipated cavernous sinus involvement. The patient declined further surgery. This was the only patient who had persistent disease. Preoperative and intraoperative management, blood loss, complications, and residual effects are described.

AB - From 1977 to 2001, 5 patients were seen with giant angiofibromas that had intracranial penetration. Three of these had involvement of the cavernous sinus with angiographic evidence of significant blood supply to the tumor. We attempted complete tumor removal in all patients via a skull-base procedure. The infratemporal fossa/middle fossa approach was used in 3 patients, an anterior craniofacial approach in 1, and an anterior subcranial approach in 1. Complete tumor removal was achieved in 4 patients and incomplete excision in 1. The latter was attempted with an anterior subcranial approach but required an infratemporal fossa/middle fossa approach for completion because of unanticipated cavernous sinus involvement. The patient declined further surgery. This was the only patient who had persistent disease. Preoperative and intraoperative management, blood loss, complications, and residual effects are described.

UR - http://www.scopus.com/inward/record.url?scp=3142779261&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=3142779261&partnerID=8YFLogxK

U2 - 10.1001/archotol.130.7.882

DO - 10.1001/archotol.130.7.882

M3 - Article

VL - 130

SP - 882

EP - 886

JO - JAMA Otolaryngology - Head and Neck Surgery

JF - JAMA Otolaryngology - Head and Neck Surgery

SN - 2168-6181

IS - 7

ER -