Giant cell tumor of soft parts: a report of an equine and a feline case

G. H. Ford, R. N. Empson, Charles Plopper, P. H. Brown

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Masses removed from the superficial fascia of the jugular groove of a 12 year old Arabian mare and from the femoral canal of a 7 1/2 year old female cat appeared to be counterparts of the human malignant giant cell tumor of soft parts, even recapitulating the clinical behavior of the respective subgroups. Histologically, both neoplasms contained the characteristic features of the malignant giant cell tumor of soft parts: large multinucleate giant cells, pleomorphic mononuclear giant cells, histiocytes, fibroblasts and fibrocytes that were sometimes sarcomatous, and foci of hemorrhage and necrosis. Ultrastructural characteristics of the giant cells suggest mesenchymal origin with osteoblastic or chondroblastic differentiation.

Original languageEnglish (US)
Pages (from-to)428-433
Number of pages6
JournalVeterinary Pathology
Volume12
Issue number5-6
DOIs
StatePublished - Jan 1 1975
Externally publishedYes

ASJC Scopus subject areas

  • veterinary(all)

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