Giant cell tumor of soft parts: a report of an equine and a feline case

G. H. Ford, R. N. Empson, Charles Plopper, P. H. Brown

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Masses removed from the superficial fascia of the jugular groove of a 12 year old Arabian mare and from the femoral canal of a 7 1/2 year old female cat appeared to be counterparts of the human malignant giant cell tumor of soft parts, even recapitulating the clinical behavior of the respective subgroups. Histologically, both neoplasms contained the characteristic features of the malignant giant cell tumor of soft parts: large multinucleate giant cells, pleomorphic mononuclear giant cells, histiocytes, fibroblasts and fibrocytes that were sometimes sarcomatous, and foci of hemorrhage and necrosis. Ultrastructural characteristics of the giant cells suggest mesenchymal origin with osteoblastic or chondroblastic differentiation.

Original languageEnglish (US)
Pages (from-to)428-433
Number of pages6
JournalVeterinary Pathology
Volume12
Issue number5-6
DOIs
StatePublished - Jan 1 1975
Externally publishedYes

Fingerprint

Giant Cell Tumors
Felidae
giant cells
Giant Cells
Horses
cats
horses
neoplasms
Histiocytes
Subcutaneous Tissue
Thigh
Arabian (horse breed)
histiocytes
Cats
Necrosis
Neck
fascia
Fibroblasts
Hemorrhage
thighs

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Giant cell tumor of soft parts : a report of an equine and a feline case. / Ford, G. H.; Empson, R. N.; Plopper, Charles; Brown, P. H.

In: Veterinary Pathology, Vol. 12, No. 5-6, 01.01.1975, p. 428-433.

Research output: Contribution to journalArticle

Ford, G. H. ; Empson, R. N. ; Plopper, Charles ; Brown, P. H. / Giant cell tumor of soft parts : a report of an equine and a feline case. In: Veterinary Pathology. 1975 ; Vol. 12, No. 5-6. pp. 428-433.
@article{2eec792b994e41c9a0a9d7ef29340f96,
title = "Giant cell tumor of soft parts: a report of an equine and a feline case",
abstract = "Masses removed from the superficial fascia of the jugular groove of a 12 year old Arabian mare and from the femoral canal of a 7 1/2 year old female cat appeared to be counterparts of the human malignant giant cell tumor of soft parts, even recapitulating the clinical behavior of the respective subgroups. Histologically, both neoplasms contained the characteristic features of the malignant giant cell tumor of soft parts: large multinucleate giant cells, pleomorphic mononuclear giant cells, histiocytes, fibroblasts and fibrocytes that were sometimes sarcomatous, and foci of hemorrhage and necrosis. Ultrastructural characteristics of the giant cells suggest mesenchymal origin with osteoblastic or chondroblastic differentiation.",
author = "Ford, {G. H.} and Empson, {R. N.} and Charles Plopper and Brown, {P. H.}",
year = "1975",
month = "1",
day = "1",
doi = "10.1177/0300985875012005-00609",
language = "English (US)",
volume = "12",
pages = "428--433",
journal = "Veterinary Pathology",
issn = "0300-9858",
publisher = "SAGE Publications Ltd",
number = "5-6",

}

TY - JOUR

T1 - Giant cell tumor of soft parts

T2 - a report of an equine and a feline case

AU - Ford, G. H.

AU - Empson, R. N.

AU - Plopper, Charles

AU - Brown, P. H.

PY - 1975/1/1

Y1 - 1975/1/1

N2 - Masses removed from the superficial fascia of the jugular groove of a 12 year old Arabian mare and from the femoral canal of a 7 1/2 year old female cat appeared to be counterparts of the human malignant giant cell tumor of soft parts, even recapitulating the clinical behavior of the respective subgroups. Histologically, both neoplasms contained the characteristic features of the malignant giant cell tumor of soft parts: large multinucleate giant cells, pleomorphic mononuclear giant cells, histiocytes, fibroblasts and fibrocytes that were sometimes sarcomatous, and foci of hemorrhage and necrosis. Ultrastructural characteristics of the giant cells suggest mesenchymal origin with osteoblastic or chondroblastic differentiation.

AB - Masses removed from the superficial fascia of the jugular groove of a 12 year old Arabian mare and from the femoral canal of a 7 1/2 year old female cat appeared to be counterparts of the human malignant giant cell tumor of soft parts, even recapitulating the clinical behavior of the respective subgroups. Histologically, both neoplasms contained the characteristic features of the malignant giant cell tumor of soft parts: large multinucleate giant cells, pleomorphic mononuclear giant cells, histiocytes, fibroblasts and fibrocytes that were sometimes sarcomatous, and foci of hemorrhage and necrosis. Ultrastructural characteristics of the giant cells suggest mesenchymal origin with osteoblastic or chondroblastic differentiation.

UR - http://www.scopus.com/inward/record.url?scp=0016642022&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016642022&partnerID=8YFLogxK

U2 - 10.1177/0300985875012005-00609

DO - 10.1177/0300985875012005-00609

M3 - Article

C2 - 1229057

AN - SCOPUS:0016642022

VL - 12

SP - 428

EP - 433

JO - Veterinary Pathology

JF - Veterinary Pathology

SN - 0300-9858

IS - 5-6

ER -