Genomic approaches in breast cancer research

Henry J. Donahue, Damian C Genetos

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Microarray technologies provide high-throughput analysis of genes that are differentially expressed in humans and other species, and thereby provide a means to measure how biological systems are altered during development or disease states. Within, we review how high-throughput genomic technologies have increased our understanding about the molecular complexity of breast cancer, identified distinct molecular phenotypes and how they can be used to increase the accuracy of predicted clinical outcome.

Original languageEnglish (US)
Pages (from-to)391-396
Number of pages6
JournalBriefings in Functional Genomics
Volume12
Issue number5
DOIs
StatePublished - Sep 2013

Keywords

  • Breast cancer
  • Genomics
  • Histology
  • Microarray
  • Tumor

ASJC Scopus subject areas

  • Biochemistry
  • Genetics
  • Molecular Biology

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