Abstract
A genome-wide association screen for primary biliary cirrhosis risk alleles was performed in an Italian cohort. The results from the Italian cohort replicated IL12A and IL12RB associations, and a combined meta-analysis using a Canadian dataset identified newly associated loci at SPIB (P = 7.9 × 10-11, odds ratio (OR) = 1.46), IRF5-TNPO3 (P = 2.8 × 10 -10, OR = 1.63) and 17q12-21 (P = 1.7 × 10-10, OR = 1.38).
Original language | English (US) |
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Pages (from-to) | 658-660 |
Number of pages | 3 |
Journal | Nature Genetics |
Volume | 42 |
Issue number | 8 |
DOIs | |
State | Published - Aug 2010 |
ASJC Scopus subject areas
- Genetics