Genome surfing: Using internet-based informatic tools toward functional genetic studies in mouse and humans

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

The wealth of databases containing genomic information and the easy access via the internet can be an invaluable tool in performing genetic studies and identifying important sequences. This article provides an overview and specific methods for using these resources in both positional cloning and identifying candidate genes for diseases and phenotypes. The ability to apply information across the mouse and human species is stressed. Useful internet sites and their contents are identified and described, and some understanding of their current limitations is provided. As additional genomic definition accelerates, the use of these tools will become more essential in cutting edge research linking sequence and function in whole mammalian organisms.

Original languageEnglish (US)
Pages (from-to)445-457
Number of pages13
JournalMethods: A Companion to Methods in Enzymology
Volume13
Issue number4
DOIs
StatePublished - Dec 1997

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)

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