Genome size and complexity of the obligate fungal pathogen, Bremia lactucae

David M. Francis, Scot H. Hulbert, Richard W Michelmore

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


The size and organization of the genome of Bremia lactucae, a highly specialized fungal pathogen of lettuce, has been characterized using dot blot genomic reconstructions, reverse genomic blots, and genomic DNA reassociation kinetics. The haploid genome contains 5 × 107 bp of DNA and 65% of the nuclear DNA is repeated. Low copy sequences are interspersed with repeated sequences in a short-period interspersion pattern. This pattern of genome organization is different to that described for other fungi. Although most fungi have been shown to contain some form of repetitive DNA other than the ribosomal repeat, the high percentage of repetitive DNA and the interspersion of low copy and repeated sequences are atypical of fungi characterized previously.

Original languageEnglish (US)
Pages (from-to)299-309
Number of pages11
JournalExperimental Mycology
Issue number4
StatePublished - 1990


  • Bremia lactucae
  • gene-for-gene
  • genome complexity
  • genome size
  • Lactuca sativa
  • lettuce
  • Oomycete
  • repetitive DNA

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology


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