Genetics of Major Insect Vectors

P. L. Dorn, S. Justi, E. S. Krafsur, Gregory C Lanzaro, A. J. Cornel, Yoosook Lee, C. A. Hill

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Vector-borne diseases remain a major cause of human and animal morbidity and mortality contributing to immeasurable suffering while impeding economic development. Without available and accessible vaccines and effective treatments for affected people, targeting the insect vectors to block pathogen transmission continues to be the only efficacious intervention. Understanding the genetics of the insect vectors provides important information needed for successful disease control. In this chapter the authors review what is known about the genetics of four major insect vector groups-tsetse flies, which carry African trypanosomiasis, triatomine bugs, carriers of American trypanosomiasis or Chagas disease, anopheline mosquitoes, the vectors of malaria, and ticks, vectors of a variety of pathogens. Biogeography, phylogeny and systematics, cytogenetics, population genetics, and genomics for these vectors are reviewed. In addition, the authors describe new research tools that may in the future provide more effective disease management.

Original languageEnglish (US)
Title of host publicationGenetics and Evolution of Infectious Diseases
Subtitle of host publicationSecond Edition
PublisherElsevier Inc.
Pages341-382
Number of pages42
ISBN (Print)9780127999425
DOIs
StatePublished - Feb 8 2017

Keywords

  • African trypanosomiasis
  • Anopheles
  • Arboviruses
  • Babesiosis
  • Chagas disease
  • Genetics
  • Glossina
  • Ixodida
  • Lyme disease
  • Malaria
  • Mites
  • Ticks
  • Triatominae
  • Tsetse
  • Vector-borne disease

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Dorn, P. L., Justi, S., Krafsur, E. S., Lanzaro, G. C., Cornel, A. J., Lee, Y., & Hill, C. A. (2017). Genetics of Major Insect Vectors. In Genetics and Evolution of Infectious Diseases: Second Edition (pp. 341-382). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-799942-5.00015-9