Genetics of heat-curability of killer virus of yeast

L. A. Weinstein, F. Capaldo-Kimball, Michael J Leibowitz

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


The cytoplasmically inherited M double-stranded (ds) RNA genome segment of killer virus of Saccharomyces cerevisiae is heat-curable in some yeast strains but not in others. Temperature sensitivity is conferred on both M1 and M2 dsRNA satellite virus segments by the L-A-HN allele of the killer helper virus genome, but not by the L-A-H allele. Both diploidy and mating type heterozygosity of the host cell are also correlated with increased virus curability.

Original languageEnglish (US)
Pages (from-to)411-418
Number of pages8
Issue number4
StatePublished - 1993
Externally publishedYes


  • L-A virus
  • non-Mendelian genetics
  • Saccharomyces cerevisiae
  • Yeast killer system

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Biotechnology
  • Bioengineering
  • Microbiology


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