Abstract
A cluster (D1Lubl) of a long-range repeat family was mapped to the proximal part of the Giemsa-negative band D in Chromosome 1 of Mus musculus and M. spretus by in situ hybridization with cloned probes of the long-range repeat family. By making use of restriction fragment length polymorphisms in DNAs from interspecific backcross mice, the cluster could be mapped to a position 5.3 ± 2.1 cM distal to the Inha locus and the same distance proximal to the Bcl-2 locus. D1Lubl was inseparable in 114 meiotic events from Acrg, Sag, and Akp-3. Taken together, the data may serve as a reference for coordinating the genetic and cytogenetic maps of Mus Chromosome 1. High-copy-number variants of the cluster, which appear cytogenetically as homogeneously staining regions at the same chromosome location, presumably arose by amplification of the long-range repeat family in situ.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 128-130 |
| Number of pages | 3 |
| Journal | Cytogenetics and Cell Genetics |
| Volume | 60 |
| Issue number | 2 |
| State | Published - 1992 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Genetics
- Cell Biology
Cite this
Genetic mapping and assignment of a long-range repeat cluster to band D of chromosome 1 in Mus musculus and M. spretus. / Traut, W.; Seldin, Michael F; Winking, H.
In: Cytogenetics and Cell Genetics, Vol. 60, No. 2, 1992, p. 128-130.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Genetic mapping and assignment of a long-range repeat cluster to band D of chromosome 1 in Mus musculus and M. spretus
AU - Traut, W.
AU - Seldin, Michael F
AU - Winking, H.
PY - 1992
Y1 - 1992
N2 - A cluster (D1Lubl) of a long-range repeat family was mapped to the proximal part of the Giemsa-negative band D in Chromosome 1 of Mus musculus and M. spretus by in situ hybridization with cloned probes of the long-range repeat family. By making use of restriction fragment length polymorphisms in DNAs from interspecific backcross mice, the cluster could be mapped to a position 5.3 ± 2.1 cM distal to the Inha locus and the same distance proximal to the Bcl-2 locus. D1Lubl was inseparable in 114 meiotic events from Acrg, Sag, and Akp-3. Taken together, the data may serve as a reference for coordinating the genetic and cytogenetic maps of Mus Chromosome 1. High-copy-number variants of the cluster, which appear cytogenetically as homogeneously staining regions at the same chromosome location, presumably arose by amplification of the long-range repeat family in situ.
AB - A cluster (D1Lubl) of a long-range repeat family was mapped to the proximal part of the Giemsa-negative band D in Chromosome 1 of Mus musculus and M. spretus by in situ hybridization with cloned probes of the long-range repeat family. By making use of restriction fragment length polymorphisms in DNAs from interspecific backcross mice, the cluster could be mapped to a position 5.3 ± 2.1 cM distal to the Inha locus and the same distance proximal to the Bcl-2 locus. D1Lubl was inseparable in 114 meiotic events from Acrg, Sag, and Akp-3. Taken together, the data may serve as a reference for coordinating the genetic and cytogenetic maps of Mus Chromosome 1. High-copy-number variants of the cluster, which appear cytogenetically as homogeneously staining regions at the same chromosome location, presumably arose by amplification of the long-range repeat family in situ.
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UR - http://www.scopus.com/inward/citedby.url?scp=0026753897&partnerID=8YFLogxK
M3 - Article
C2 - 1611911
AN - SCOPUS:0026753897
VL - 60
SP - 128
EP - 130
JO - Cytogenetic and Genome Research
JF - Cytogenetic and Genome Research
SN - 1424-8581
IS - 2
ER -