Abstract
Correlational analysis of normalized regional cerebral metabolic data obtained by positron emission tomography, in healthy subjects in the 'resting' state (eyes covered, ears plugged) using [18F]2-fluuro-2-deoxy-dgllucose, demonstrated gender differences in patterns of functional associations. Fifteen women and 18 men (< 40 yr) were scanned with a Scanditronix PC1024-7B tomograph. The brain was divided into 65 regions of interest (ROIs). There were no differences between men and women in global or regional metabolic rates, or in metabolic right-left asymmetries. Although the total number of significant correlations did not differ between men and women, patterns differed: female correlations rF were more positive than male correlations rM more often than rM > rF; and most rF > rM cases involved left frontal and sensorimotor ROIs, whereas most rM > rF cases involved right sensorimotor and occipital ROIs. The finding demonstrate gender differences in the pattern of functional neocortical interactions at the 'resting' state.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 198-208 |
| Number of pages | 11 |
| Journal | Brain Research |
| Volume | 574 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - Mar 6 1992 |
| Externally published | Yes |
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Keywords
- Brain
- Cerebral metabolism
- Correlation
- Gender
- Glucose
- Human
- Positron emission tomography
ASJC Scopus subject areas
- Developmental Biology
- Molecular Biology
- Clinical Neurology
- Neuroscience(all)
Cite this
Gender differences in correlations of cerebral glucose matabolic rates in young normal adults. / Azari, N. P.; Rapoport, S. I.; Grady, C. L.; DeCarli, Charles; Haxby, J. V.; Schapiro, M. B.; Horwitz, B.
In: Brain Research, Vol. 574, No. 1-2, 06.03.1992, p. 198-208.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Gender differences in correlations of cerebral glucose matabolic rates in young normal adults
AU - Azari, N. P.
AU - Rapoport, S. I.
AU - Grady, C. L.
AU - DeCarli, Charles
AU - Haxby, J. V.
AU - Schapiro, M. B.
AU - Horwitz, B.
PY - 1992/3/6
Y1 - 1992/3/6
N2 - Correlational analysis of normalized regional cerebral metabolic data obtained by positron emission tomography, in healthy subjects in the 'resting' state (eyes covered, ears plugged) using [18F]2-fluuro-2-deoxy-dgllucose, demonstrated gender differences in patterns of functional associations. Fifteen women and 18 men (< 40 yr) were scanned with a Scanditronix PC1024-7B tomograph. The brain was divided into 65 regions of interest (ROIs). There were no differences between men and women in global or regional metabolic rates, or in metabolic right-left asymmetries. Although the total number of significant correlations did not differ between men and women, patterns differed: female correlations rF were more positive than male correlations rM more often than rM > rF; and most rF > rM cases involved left frontal and sensorimotor ROIs, whereas most rM > rF cases involved right sensorimotor and occipital ROIs. The finding demonstrate gender differences in the pattern of functional neocortical interactions at the 'resting' state.
AB - Correlational analysis of normalized regional cerebral metabolic data obtained by positron emission tomography, in healthy subjects in the 'resting' state (eyes covered, ears plugged) using [18F]2-fluuro-2-deoxy-dgllucose, demonstrated gender differences in patterns of functional associations. Fifteen women and 18 men (< 40 yr) were scanned with a Scanditronix PC1024-7B tomograph. The brain was divided into 65 regions of interest (ROIs). There were no differences between men and women in global or regional metabolic rates, or in metabolic right-left asymmetries. Although the total number of significant correlations did not differ between men and women, patterns differed: female correlations rF were more positive than male correlations rM more often than rM > rF; and most rF > rM cases involved left frontal and sensorimotor ROIs, whereas most rM > rF cases involved right sensorimotor and occipital ROIs. The finding demonstrate gender differences in the pattern of functional neocortical interactions at the 'resting' state.
KW - Brain
KW - Cerebral metabolism
KW - Correlation
KW - Gender
KW - Glucose
KW - Human
KW - Positron emission tomography
UR - http://www.scopus.com/inward/record.url?scp=0026506684&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026506684&partnerID=8YFLogxK
U2 - 10.1016/0006-8993(92)90817-S
DO - 10.1016/0006-8993(92)90817-S
M3 - Article
C2 - 1638393
AN - SCOPUS:0026506684
VL - 574
SP - 198
EP - 208
JO - Brain Research
JF - Brain Research
SN - 0006-8993
IS - 1-2
ER -