Abstract
Correlational analysis of normalized regional cerebral metabolic data obtained by positron emission tomography, in healthy subjects in the 'resting' state (eyes covered, ears plugged) using [18F]2-fluuro-2-deoxy-dgllucose, demonstrated gender differences in patterns of functional associations. Fifteen women and 18 men (< 40 yr) were scanned with a Scanditronix PC1024-7B tomograph. The brain was divided into 65 regions of interest (ROIs). There were no differences between men and women in global or regional metabolic rates, or in metabolic right-left asymmetries. Although the total number of significant correlations did not differ between men and women, patterns differed: female correlations rF were more positive than male correlations rM more often than rM > rF; and most rF > rM cases involved left frontal and sensorimotor ROIs, whereas most rM > rF cases involved right sensorimotor and occipital ROIs. The finding demonstrate gender differences in the pattern of functional neocortical interactions at the 'resting' state.
Original language | English (US) |
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Pages (from-to) | 198-208 |
Number of pages | 11 |
Journal | Brain Research |
Volume | 574 |
Issue number | 1-2 |
DOIs | |
State | Published - Mar 6 1992 |
Externally published | Yes |
Keywords
- Brain
- Cerebral metabolism
- Correlation
- Gender
- Glucose
- Human
- Positron emission tomography
ASJC Scopus subject areas
- Developmental Biology
- Molecular Biology
- Clinical Neurology
- Neuroscience(all)