Gelatinous transformation of bone marrow in a rabbit

Flavio H. Alonso, Danielle K. Tarbert, Bin Xi Wu, Paula Rodriguez, Mary M. Christopher

Research output: Contribution to journalArticlepeer-review

Abstract

A 9-y-old, spayed female rabbit was presented for evaluation of hypoglycemia and lateral recumbency. The patient was hypothermic and had diffuse muscle wasting; weight loss since a previous visit was also noted. Hematologic abnormalities included progressive nonregenerative anemia and severe heteropenia. Evaluation of a bone marrow aspirate sample revealed active hematopoiesis with abundant pink matrix. The matrix material stained positively with periodic acid–Schiff and alcian blue, and a diagnosis of gelatinous transformation of the bone marrow (GTBM, serous atrophy of fat) was made. Although its precise prevalence remains to be determined, GTBM should be suspected in rabbits with persistent cytopenias following prolonged starvation or gastrointestinal disease.

Original languageEnglish (US)
Pages (from-to)1183-1187
Number of pages5
JournalJournal of Veterinary Diagnostic Investigation
Volume33
Issue number6
DOIs
StatePublished - Nov 2021

Keywords

  • heteropenia
  • nonregenerative anemia
  • pancytopenia
  • rabbits
  • starvation

ASJC Scopus subject areas

  • veterinary(all)

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