Gastrointestinal stromal tumor presenting as pancreatic mass: A case report and review of the literature

A 72-year-old female is described herein who presented with chronic right upper quadrant abdominal pain and obstructive jaundice. CT scan revealed a solid mass in the region of the pancreatic head, causing concern for malignancy of the pancreas. Endoscopic ultrasound-guided fine needle aspiration of the lesion with immunohistochemical staining was essential in clarifying the diagnosis, demonstrating findings consistent with a gastrointestinal stromal tumor (GIST). This was verified following a pancreaticoduodenectomy revealing a large GIST arising from the duodenum and invading the pancreatic head. Review of the literature reveals the current case is an exceedingly rare presentation of a small bowel GIST.