Gastrointestinal secretion of intravenously injected barium chloride has been measured in mice using twenty-four hour total body retention of radioactive barium-135m. Various drugs were used in an attempt to suppress the gastrointestinal secretion of barium. Orally administered magnesium sulfate and intravenously injected calcium gluconate increased the total body retention of barium-135m from a normal 55% to about 80%. This increased retention occurred because these agents are known to suppress the gastrointestinal secretion of barium-135m. The use of these agents might help improve bone scans with radioactive barium. Radioactive barium may be used under experimental conditions to study normal and abnormal gastrointestinal secretion.
|Original language||English (US)|
|Title of host publication||American Journal of Proctology Gastroenterology and Colon and Rectal Surgery|
|Number of pages||2|
|State||Published - 1980|
ASJC Scopus subject areas