Gastroenteritis of basenji dogs.

Nigel J Maclachlan, E. B. Breitschwerdt, J. M. Chambers, R. A. Argenzio, E. V. De Buysscher

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Intestinal digestive and absorptive function and the gross and histologic appearance of the gastrointestinal tract were evaluated in Basenji dogs with chronic diarrhea, asymptomatic Basenji dogs, and healthy control dogs. Gastric rugal hypertrophy, lymphocytic gastritis, and gastric mucosal atrophy occurred in asymptomatic and affected Basenji dogs. All affected dogs had moderate or severe intestinal lesions characterized by villous clubbing and fusion, increased tortuosity of intestinal crypts, and diffuse infiltration of mononuclear inflammatory cells. Intestinal lesions in asymptomatic Basenji dogs invariably were less severe than those in affected dogs, but the small intestinal lamina propria of asymptomatic Basenji dogs consistently contained greater numbers of mononuclear inflammatory cells than did that of control dogs. The proportion of cells containing each immunoglobulin isotype (IgG, IgM, IgA) was similar among affected Basenji dogs, asymptomatic Basenji dogs, and control dogs. As compared to healthy beagle controls, intestinal function was abnormal in both affected and asymptomatic Basenji dogs evaluated by combined N-benzoyl-L-tyrosyl-p-aminobenzoic acid and d-xylose test, but malabsorption and maldigestion were most pronounced in affected Basenji dogs.

Original languageEnglish (US)
Pages (from-to)36-41
Number of pages6
JournalVeterinary Pathology
Volume25
Issue number1
StatePublished - Jan 1988
Externally publishedYes

Fingerprint

gastroenteritis
Gastroenteritis
Dogs
dogs
lesions (animal)
Stomach
stomach
p-aminobenzoic acid
intestinal crypts
gastritis
malabsorption
Immunoglobulin Isotypes
Xylose
laminae (animals)
Gastritis
cells
Beagle
atrophy
xylose
hypertrophy

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Maclachlan, N. J., Breitschwerdt, E. B., Chambers, J. M., Argenzio, R. A., & De Buysscher, E. V. (1988). Gastroenteritis of basenji dogs. Veterinary Pathology, 25(1), 36-41.

Gastroenteritis of basenji dogs. / Maclachlan, Nigel J; Breitschwerdt, E. B.; Chambers, J. M.; Argenzio, R. A.; De Buysscher, E. V.

In: Veterinary Pathology, Vol. 25, No. 1, 01.1988, p. 36-41.

Research output: Contribution to journalArticle

Maclachlan, NJ, Breitschwerdt, EB, Chambers, JM, Argenzio, RA & De Buysscher, EV 1988, 'Gastroenteritis of basenji dogs.', Veterinary Pathology, vol. 25, no. 1, pp. 36-41.
Maclachlan NJ, Breitschwerdt EB, Chambers JM, Argenzio RA, De Buysscher EV. Gastroenteritis of basenji dogs. Veterinary Pathology. 1988 Jan;25(1):36-41.
Maclachlan, Nigel J ; Breitschwerdt, E. B. ; Chambers, J. M. ; Argenzio, R. A. ; De Buysscher, E. V. / Gastroenteritis of basenji dogs. In: Veterinary Pathology. 1988 ; Vol. 25, No. 1. pp. 36-41.
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