Gastric mucosal barrier, drug induced acute erosive gastritis and stress ulcer

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Gastric mucin probably plays an insignificant role in the protection of gastric mucosa. The metabolic integrity of the mucosal cells is important in the maintenance of the gastric mucosal barrier. Various drugs and 'stress' break the gastric mucosal barrier, allowing increased back diffusion of hydrogen ions and causing gastric erosions, stress ulcers, and gastric bleeding. Presence of acid seems to be necessary for the occurrence of these lesions. Acute gastric mucosal lesions as a cause of upper gastrointestinal bleeding are best diagnosed by fiberoptic endoscopy. Antacids may be effective in preventing these lesions.

Original languageEnglish (US)
Pages (from-to)1179-1182
Number of pages4
JournalSouthern Medical Journal
Volume70
Issue number10
StatePublished - 1977
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Gastric mucosal barrier, drug induced acute erosive gastritis and stress ulcer'. Together they form a unique fingerprint.

  • Cite this