Gastric acid and digestive physiology

Philip T. Ramsay, Aaron Carr

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

The primary function of the stomach is to prepare food for digestion and absorption by the intestine. Acid production is the unique and central component of the stomach's contribution to the digestive process. Acid bathes the food bolus while stored in the stomach, facilitating digestion. An intact defense against mucosal damage by the stomach's acid is essential to avoid ulceration. This article focuses on the physiology of gastric acid production, the stomach's defense mechanisms against acid injury, and the most common challenges to the gastric defenses. A brief description of the stomach's nonacid digestive capabilities is included.

Original languageEnglish (US)
Pages (from-to)977-982
Number of pages6
JournalSurgical Clinics of North America
Volume91
Issue number5
DOIs
StatePublished - Oct 2011
Externally publishedYes

Keywords

  • Digestive physiology
  • Gastric acid
  • Stomach

ASJC Scopus subject areas

  • Surgery

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