Gas gangrene in mammals: a review

Carlos A.Oliveira Junior, Rodrigo O.S. Silva, Francisco C.F. Lobato, Mauricio A. Navarro, Francisco A. Uzal

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Gas gangrene is a necrotizing infection of subcutaneous tissue and muscle that affects mainly ruminants and horses, but also other domestic and wild mammals. Clostridium chauvoei, C. septicum, C. novyi type A, C. perfringens type A, and C. sordellii are the etiologic agents of this disease, acting singly or in combination. Although a presumptive diagnosis of gas gangrene can be established based on clinical history, clinical signs, and gross and microscopic changes, identification of the clostridia involved is required for confirmatory diagnosis. Gross and microscopic lesions are, however, highly suggestive of the disease. Although the disease has a worldwide distribution and can cause significant economic losses, the literature is limited mostly to case reports. Thus, we have reviewed the current knowledge of gas gangrene in mammals.

Original languageEnglish (US)
Pages (from-to)175-183
Number of pages9
JournalJournal of Veterinary Diagnostic Investigation
Issue number2
StatePublished - Mar 1 2020


  • cattle
  • clostridia
  • gas gangrene
  • horses
  • sheep

ASJC Scopus subject areas

  • veterinary(all)


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