Gallate Contact Dermatitis: Product Update and Systematic Review

Zachary E. Holcomb, Megan G. Van Noord, Amber Reck Atwater

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

Allergic contact dermatitis related to cosmetic use can result from allergens not routinely evaluated by standard patch test protocols. Propyl, octyl, and dodecyl gallates are commonly used antioxidant preservatives with reports of associated allergic contact dermatitis in the literature. The objectives of this review were to investigate the role of gallates in allergic contact dermatitis and to explore products containing these preservatives. A systematic review of the literature through April 2016 was performed to explore cases of reported gallate allergy. Food and cosmetic product databases were searched for products containing gallates. Seventy-four cases of gallate contact allergy have been reported. In addition, a variety of commercially available cosmetic products and foods contain gallate chemicals. Propyl gallate is the most commonly reported gallate contact allergen and often causes facial and/or hand dermatitis.

Original languageEnglish (US)
Pages (from-to)115-127
Number of pages13
JournalDermatitis
Volume28
Issue number2
DOIs
StatePublished - Mar 1 2017
Externally publishedYes

Fingerprint

Allergic Contact Dermatitis
Contact Dermatitis
Propyl Gallate
Cosmetics
Allergens
Hypersensitivity
Food
Patch Tests
Dermatitis
Hand
Antioxidants
Databases

ASJC Scopus subject areas

  • Immunology and Allergy
  • Dermatology

Cite this

Gallate Contact Dermatitis : Product Update and Systematic Review. / Holcomb, Zachary E.; Van Noord, Megan G.; Atwater, Amber Reck.

In: Dermatitis, Vol. 28, No. 2, 01.03.2017, p. 115-127.

Research output: Contribution to journalReview article

Holcomb, Zachary E. ; Van Noord, Megan G. ; Atwater, Amber Reck. / Gallate Contact Dermatitis : Product Update and Systematic Review. In: Dermatitis. 2017 ; Vol. 28, No. 2. pp. 115-127.
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