Abstract
Fungal infections of the nose and paranasal sinuses represent a spectrum of diseases ranging from colonization to invasive rhinosinusitis. Clinical manifestations are largely dependent on the immune status of the host, and given the ubiquitous nature of these organisms, exposure is unavoidable. Noninvasive disease includes asymptomatic fungal colonization, fungus balls, and allergic fungal rhinosinusitis. Invasive disease includes indolent chronic rhinosinusitis, granulomatous fungal sinusitis, and acute fulminant fungal rhinosinusitis. A differentiation of these somewhat overlapping syndromes and the disparate treatment regimens required for effective management are the focus of this review.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 321-326 |
| Number of pages | 6 |
| Journal | Journal of Allergy and Clinical Immunology |
| Volume | 129 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 2012 |
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Keywords
- acute fulminant fungal rhinosinusitis
- allergic fungal rhinosinusitis
- chronic rhinosinusitis
- Fungal colonization
- fungus balls
- granulomatous fungal sinusitis
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
Cite this
Fungal disease of the nose and paranasal sinuses. / Thompson, George Richard; Patterson, Thomas F.
In: Journal of Allergy and Clinical Immunology, Vol. 129, No. 2, 02.2012, p. 321-326.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Fungal disease of the nose and paranasal sinuses
AU - Thompson, George Richard
AU - Patterson, Thomas F.
PY - 2012/2
Y1 - 2012/2
N2 - Fungal infections of the nose and paranasal sinuses represent a spectrum of diseases ranging from colonization to invasive rhinosinusitis. Clinical manifestations are largely dependent on the immune status of the host, and given the ubiquitous nature of these organisms, exposure is unavoidable. Noninvasive disease includes asymptomatic fungal colonization, fungus balls, and allergic fungal rhinosinusitis. Invasive disease includes indolent chronic rhinosinusitis, granulomatous fungal sinusitis, and acute fulminant fungal rhinosinusitis. A differentiation of these somewhat overlapping syndromes and the disparate treatment regimens required for effective management are the focus of this review.
AB - Fungal infections of the nose and paranasal sinuses represent a spectrum of diseases ranging from colonization to invasive rhinosinusitis. Clinical manifestations are largely dependent on the immune status of the host, and given the ubiquitous nature of these organisms, exposure is unavoidable. Noninvasive disease includes asymptomatic fungal colonization, fungus balls, and allergic fungal rhinosinusitis. Invasive disease includes indolent chronic rhinosinusitis, granulomatous fungal sinusitis, and acute fulminant fungal rhinosinusitis. A differentiation of these somewhat overlapping syndromes and the disparate treatment regimens required for effective management are the focus of this review.
KW - acute fulminant fungal rhinosinusitis
KW - allergic fungal rhinosinusitis
KW - chronic rhinosinusitis
KW - Fungal colonization
KW - fungus balls
KW - granulomatous fungal sinusitis
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U2 - 10.1016/j.jaci.2011.11.039
DO - 10.1016/j.jaci.2011.11.039
M3 - Article
VL - 129
SP - 321
EP - 326
JO - Journal of Allergy and Clinical Immunology
JF - Journal of Allergy and Clinical Immunology
SN - 0091-6749
IS - 2
ER -