Fundamentals of antibody-related therapy and diagnostics

Huguette Albrecht, James A. Rodosevich, Michael Babich

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Antibodies for therapy and diagnostics form one of the fastest growing segments of the pharmaceutical market. The combination of hybridoma and recombinant DNA technologies have led to an increased production of monoclonal antibodies (MAbs), including fully human MAbs, that can be tailored for specific applications. With advances in imaging methods, MAbs are increasingly used os in vivo diagnostic tools. Therapeutic MAbs, used to treat cancer and autoimmune diseases, have proven beneficial in the clinic. An overview is presented of the history, current state and future perspectives of this emergent field.

Original languageEnglish (US)
Pages (from-to)199-211
Number of pages13
JournalDrugs of Today
Volume45
Issue number3
DOIs
StatePublished - Mar 2009

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ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

Albrecht, H., Rodosevich, J. A., & Babich, M. (2009). Fundamentals of antibody-related therapy and diagnostics. Drugs of Today, 45(3), 199-211. https://doi.org/101358/dot20094531341343