Fundamental limits of positron emission mammography

W. W. Moses, J. Qi

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


We explore the causes of performance limitation in positron emission mammography cameras. We compare two basic camera geometries containing the same volume of 511keV photon detectors, one with a parallel plane geometry and another with a rectangular geometry. We find that both geometries have similar performance for the phantom imaged (in Monte Carlo simulation), even though the solid angle coverage of the rectangular camera is about 50% higher than the parallel plane camera. The reconstruction algorithm used significantly affects the resulting image; iterative methods significantly outperform the commonly used focal plane tomography. Finally, the characteristics of the tumor itself, specifically the absolute amount of radiotracer taken up by the tumor, will significantly affect the imaging performance.

Original languageEnglish (US)
Pages (from-to)82-89
Number of pages8
JournalNuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Issue number1
StatePublished - Jan 21 2003
Externally publishedYes


  • Breast cancer
  • Focal plane tomography
  • Iterative reconstruction
  • Nuclear medicine instrumentation
  • Positron emission mammography
  • Positron emission tomography

ASJC Scopus subject areas

  • Instrumentation
  • Nuclear and High Energy Physics


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