Functional maps of human auditory cortex: Effects of acoustic features and attention

David L Woods, G. Christopher Stecker, Teemu Rinne, Timothy J. Herron, Anthony D. Cate, E. William Yund, Isaac Liao, Xiaojian Kang

Research output: Contribution to journalArticle

101 Citations (Scopus)

Abstract

Background: While human auditory cortex is known to contain tonotopically organized auditory cortical fields (ACFs), little is known about how processing in these fields is modulated by other acoustic features or by attention. Methodology/Principal Findings: We used functional magnetic resonance imaging (fMRI) and population-based cortical surface analysis to characterize the tonotopic organization of human auditory cortex and analyze the influence of tone intensity, ear of delivery, scanner background noise, and intermodal selective attention on auditory cortex activations. Medial auditory cortex surrounding Heschl's gyrus showed large sensory (unattended) activations with two mirror-symmetric tonotopic fields similar to those observed in non-human primates. Sensory responses in medial regions had symmetrical distributions with respect to the left and right hemispheres, were enlarged for tones of increased intensity, and were enhanced when sparse image acquisition reduced scanner acoustic noise. Spatial distribution analysis suggested that changes in tone intensity shifted activation within isofrequency bands. Activations to monaural tones were enhanced over the hemisphere contralateral to stimulation, where they produced activations similar to those produced by binaural sounds. Lateral regions of auditory cortex showed small sensory responses that were larger in the right than left hemisphere, lacked tonotopic organization, and were uninfluenced by acoustic parameters. Sensory responses in both medial and lateral auditory cortex decreased in magnitude throughout stimulus blocks. Attention-related modulations (ARMs) were larger in lateral than medial regions of auditory cortex and appeared to arise primarily in belt and parabelt auditory fields. ARMs lacked tonotopic organization, were unaffected by acoustic parameters, and had distributions that were distinct from those of sensory responses. Unlike the gradual adaptation seen for sensory responses, ARMs increased in amplitude throughout stimulus blocks. Conclusions/Significance: The results are consistent with the view that medial regions of human auditory cortex contain tonotopically organized core and belt fields that map the basic acoustic features of sounds while surrounding higher-order parabelt regions are tuned to more abstract stimulus attributes. Intermodal selective attention enhances processing in neuronal populations that are partially distinct from those activated by unattended stimuli.

Original languageEnglish (US)
Article numbere5183
JournalPLoS One
Volume4
Issue number4
DOIs
StatePublished - Apr 13 2009

Fingerprint

Auditory Cortex
Acoustics
acoustics
cortex
Chemical activation
Modulation
Acoustic waves
scanners
Image acquisition
Surface analysis
Processing
Acoustic noise
Noise
Spatial distribution
Mirrors
Spatial Analysis
magnetic resonance imaging
ears
Primates
Population

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Woods, D. L., Stecker, G. C., Rinne, T., Herron, T. J., Cate, A. D., Yund, E. W., ... Kang, X. (2009). Functional maps of human auditory cortex: Effects of acoustic features and attention. PLoS One, 4(4), [e5183]. https://doi.org/10.1371/journal.pone.0005183

Functional maps of human auditory cortex : Effects of acoustic features and attention. / Woods, David L; Stecker, G. Christopher; Rinne, Teemu; Herron, Timothy J.; Cate, Anthony D.; Yund, E. William; Liao, Isaac; Kang, Xiaojian.

In: PLoS One, Vol. 4, No. 4, e5183, 13.04.2009.

Research output: Contribution to journalArticle

Woods, DL, Stecker, GC, Rinne, T, Herron, TJ, Cate, AD, Yund, EW, Liao, I & Kang, X 2009, 'Functional maps of human auditory cortex: Effects of acoustic features and attention', PLoS One, vol. 4, no. 4, e5183. https://doi.org/10.1371/journal.pone.0005183
Woods, David L ; Stecker, G. Christopher ; Rinne, Teemu ; Herron, Timothy J. ; Cate, Anthony D. ; Yund, E. William ; Liao, Isaac ; Kang, Xiaojian. / Functional maps of human auditory cortex : Effects of acoustic features and attention. In: PLoS One. 2009 ; Vol. 4, No. 4.
@article{f75bcb1838fa49d1ad2657bb4ef48a5f,
title = "Functional maps of human auditory cortex: Effects of acoustic features and attention",
abstract = "Background: While human auditory cortex is known to contain tonotopically organized auditory cortical fields (ACFs), little is known about how processing in these fields is modulated by other acoustic features or by attention. Methodology/Principal Findings: We used functional magnetic resonance imaging (fMRI) and population-based cortical surface analysis to characterize the tonotopic organization of human auditory cortex and analyze the influence of tone intensity, ear of delivery, scanner background noise, and intermodal selective attention on auditory cortex activations. Medial auditory cortex surrounding Heschl's gyrus showed large sensory (unattended) activations with two mirror-symmetric tonotopic fields similar to those observed in non-human primates. Sensory responses in medial regions had symmetrical distributions with respect to the left and right hemispheres, were enlarged for tones of increased intensity, and were enhanced when sparse image acquisition reduced scanner acoustic noise. Spatial distribution analysis suggested that changes in tone intensity shifted activation within isofrequency bands. Activations to monaural tones were enhanced over the hemisphere contralateral to stimulation, where they produced activations similar to those produced by binaural sounds. Lateral regions of auditory cortex showed small sensory responses that were larger in the right than left hemisphere, lacked tonotopic organization, and were uninfluenced by acoustic parameters. Sensory responses in both medial and lateral auditory cortex decreased in magnitude throughout stimulus blocks. Attention-related modulations (ARMs) were larger in lateral than medial regions of auditory cortex and appeared to arise primarily in belt and parabelt auditory fields. ARMs lacked tonotopic organization, were unaffected by acoustic parameters, and had distributions that were distinct from those of sensory responses. Unlike the gradual adaptation seen for sensory responses, ARMs increased in amplitude throughout stimulus blocks. Conclusions/Significance: The results are consistent with the view that medial regions of human auditory cortex contain tonotopically organized core and belt fields that map the basic acoustic features of sounds while surrounding higher-order parabelt regions are tuned to more abstract stimulus attributes. Intermodal selective attention enhances processing in neuronal populations that are partially distinct from those activated by unattended stimuli.",
author = "Woods, {David L} and Stecker, {G. Christopher} and Teemu Rinne and Herron, {Timothy J.} and Cate, {Anthony D.} and Yund, {E. William} and Isaac Liao and Xiaojian Kang",
year = "2009",
month = "4",
day = "13",
doi = "10.1371/journal.pone.0005183",
language = "English (US)",
volume = "4",
journal = "PLoS One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "4",

}

TY - JOUR

T1 - Functional maps of human auditory cortex

T2 - Effects of acoustic features and attention

AU - Woods, David L

AU - Stecker, G. Christopher

AU - Rinne, Teemu

AU - Herron, Timothy J.

AU - Cate, Anthony D.

AU - Yund, E. William

AU - Liao, Isaac

AU - Kang, Xiaojian

PY - 2009/4/13

Y1 - 2009/4/13

N2 - Background: While human auditory cortex is known to contain tonotopically organized auditory cortical fields (ACFs), little is known about how processing in these fields is modulated by other acoustic features or by attention. Methodology/Principal Findings: We used functional magnetic resonance imaging (fMRI) and population-based cortical surface analysis to characterize the tonotopic organization of human auditory cortex and analyze the influence of tone intensity, ear of delivery, scanner background noise, and intermodal selective attention on auditory cortex activations. Medial auditory cortex surrounding Heschl's gyrus showed large sensory (unattended) activations with two mirror-symmetric tonotopic fields similar to those observed in non-human primates. Sensory responses in medial regions had symmetrical distributions with respect to the left and right hemispheres, were enlarged for tones of increased intensity, and were enhanced when sparse image acquisition reduced scanner acoustic noise. Spatial distribution analysis suggested that changes in tone intensity shifted activation within isofrequency bands. Activations to monaural tones were enhanced over the hemisphere contralateral to stimulation, where they produced activations similar to those produced by binaural sounds. Lateral regions of auditory cortex showed small sensory responses that were larger in the right than left hemisphere, lacked tonotopic organization, and were uninfluenced by acoustic parameters. Sensory responses in both medial and lateral auditory cortex decreased in magnitude throughout stimulus blocks. Attention-related modulations (ARMs) were larger in lateral than medial regions of auditory cortex and appeared to arise primarily in belt and parabelt auditory fields. ARMs lacked tonotopic organization, were unaffected by acoustic parameters, and had distributions that were distinct from those of sensory responses. Unlike the gradual adaptation seen for sensory responses, ARMs increased in amplitude throughout stimulus blocks. Conclusions/Significance: The results are consistent with the view that medial regions of human auditory cortex contain tonotopically organized core and belt fields that map the basic acoustic features of sounds while surrounding higher-order parabelt regions are tuned to more abstract stimulus attributes. Intermodal selective attention enhances processing in neuronal populations that are partially distinct from those activated by unattended stimuli.

AB - Background: While human auditory cortex is known to contain tonotopically organized auditory cortical fields (ACFs), little is known about how processing in these fields is modulated by other acoustic features or by attention. Methodology/Principal Findings: We used functional magnetic resonance imaging (fMRI) and population-based cortical surface analysis to characterize the tonotopic organization of human auditory cortex and analyze the influence of tone intensity, ear of delivery, scanner background noise, and intermodal selective attention on auditory cortex activations. Medial auditory cortex surrounding Heschl's gyrus showed large sensory (unattended) activations with two mirror-symmetric tonotopic fields similar to those observed in non-human primates. Sensory responses in medial regions had symmetrical distributions with respect to the left and right hemispheres, were enlarged for tones of increased intensity, and were enhanced when sparse image acquisition reduced scanner acoustic noise. Spatial distribution analysis suggested that changes in tone intensity shifted activation within isofrequency bands. Activations to monaural tones were enhanced over the hemisphere contralateral to stimulation, where they produced activations similar to those produced by binaural sounds. Lateral regions of auditory cortex showed small sensory responses that were larger in the right than left hemisphere, lacked tonotopic organization, and were uninfluenced by acoustic parameters. Sensory responses in both medial and lateral auditory cortex decreased in magnitude throughout stimulus blocks. Attention-related modulations (ARMs) were larger in lateral than medial regions of auditory cortex and appeared to arise primarily in belt and parabelt auditory fields. ARMs lacked tonotopic organization, were unaffected by acoustic parameters, and had distributions that were distinct from those of sensory responses. Unlike the gradual adaptation seen for sensory responses, ARMs increased in amplitude throughout stimulus blocks. Conclusions/Significance: The results are consistent with the view that medial regions of human auditory cortex contain tonotopically organized core and belt fields that map the basic acoustic features of sounds while surrounding higher-order parabelt regions are tuned to more abstract stimulus attributes. Intermodal selective attention enhances processing in neuronal populations that are partially distinct from those activated by unattended stimuli.

UR - http://www.scopus.com/inward/record.url?scp=65249171367&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=65249171367&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0005183

DO - 10.1371/journal.pone.0005183

M3 - Article

C2 - 19365552

AN - SCOPUS:65249171367

VL - 4

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 4

M1 - e5183

ER -