Abstract
Carbohydrates make up the largest component of plant-based foods and have long been known to provide fuel. However, many carbohydrates possess intrinsic biological activities that are dictated by their structures. Carbohydrates are the most abundant biopolymers in nature and are also the most structurally complicated and diverse. Consequently, the structural analysis of carbohydrates remains severely limited. To further understand their biological activities, we need new analytical tools to analyze the different classes of carbohydrates that range in size from monosaccharides to polysaccharides. These tools must be capable of rapid throughput with highly sensitive quantitation for use in clinical studies that probe their fate in human and animal fluids and tissues.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 4418-4424 |
| Number of pages | 7 |
| Journal | Journal of Agricultural and Food Chemistry |
| Volume | 67 |
| Issue number | 16 |
| DOIs | |
| State | Published - Apr 24 2019 |
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Keywords
- carbohydrate
- fiber
- human milk
- mass spectrometry
- microbiome
- monosaccharide
- oligosaccharide
- polysaccharide
- prebiotic
ASJC Scopus subject areas
- Chemistry(all)
- Agricultural and Biological Sciences(all)
Cite this
Function without Structures : The Need for In-Depth Analysis of Dietary Carbohydrates. / Amicucci, Matthew J.; Nandita, Eshani; Lebrilla, Carlito B.
In: Journal of Agricultural and Food Chemistry, Vol. 67, No. 16, 24.04.2019, p. 4418-4424.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Function without Structures
T2 - The Need for In-Depth Analysis of Dietary Carbohydrates
AU - Amicucci, Matthew J.
AU - Nandita, Eshani
AU - Lebrilla, Carlito B
PY - 2019/4/24
Y1 - 2019/4/24
N2 - Carbohydrates make up the largest component of plant-based foods and have long been known to provide fuel. However, many carbohydrates possess intrinsic biological activities that are dictated by their structures. Carbohydrates are the most abundant biopolymers in nature and are also the most structurally complicated and diverse. Consequently, the structural analysis of carbohydrates remains severely limited. To further understand their biological activities, we need new analytical tools to analyze the different classes of carbohydrates that range in size from monosaccharides to polysaccharides. These tools must be capable of rapid throughput with highly sensitive quantitation for use in clinical studies that probe their fate in human and animal fluids and tissues.
AB - Carbohydrates make up the largest component of plant-based foods and have long been known to provide fuel. However, many carbohydrates possess intrinsic biological activities that are dictated by their structures. Carbohydrates are the most abundant biopolymers in nature and are also the most structurally complicated and diverse. Consequently, the structural analysis of carbohydrates remains severely limited. To further understand their biological activities, we need new analytical tools to analyze the different classes of carbohydrates that range in size from monosaccharides to polysaccharides. These tools must be capable of rapid throughput with highly sensitive quantitation for use in clinical studies that probe their fate in human and animal fluids and tissues.
KW - carbohydrate
KW - fiber
KW - human milk
KW - mass spectrometry
KW - microbiome
KW - monosaccharide
KW - oligosaccharide
KW - polysaccharide
KW - prebiotic
UR - http://www.scopus.com/inward/record.url?scp=85064968404&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85064968404&partnerID=8YFLogxK
U2 - 10.1021/acs.jafc.9b00720
DO - 10.1021/acs.jafc.9b00720
M3 - Article
VL - 67
SP - 4418
EP - 4424
JO - Journal of Agricultural and Food Chemistry
JF - Journal of Agricultural and Food Chemistry
SN - 0021-8561
IS - 16
ER -