Abstract
This report describes recent work on a quantitative theory that relates molecular mechanisms of gene control to the organism's physiological behavior in its natural environment. When applied to catabolic operons of Escherichia coli in the human intestine, the theory predicts selection for the correct mode of gene control. It also makes surprising predictions concerning the organism's phenotype and habitat.
| Original language | English (US) |
|---|---|
| Journal | Annals of Biomedical Engineering |
| Volume | 28 |
| Issue number | SUPPL. 1 |
| State | Published - 2000 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Biomedical Engineering
Cite this
Function, design and evolution of elementary gene circuits. / Savageau, Michael.
In: Annals of Biomedical Engineering, Vol. 28, No. SUPPL. 1, 2000.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Function, design and evolution of elementary gene circuits
AU - Savageau, Michael
PY - 2000
Y1 - 2000
N2 - This report describes recent work on a quantitative theory that relates molecular mechanisms of gene control to the organism's physiological behavior in its natural environment. When applied to catabolic operons of Escherichia coli in the human intestine, the theory predicts selection for the correct mode of gene control. It also makes surprising predictions concerning the organism's phenotype and habitat.
AB - This report describes recent work on a quantitative theory that relates molecular mechanisms of gene control to the organism's physiological behavior in its natural environment. When applied to catabolic operons of Escherichia coli in the human intestine, the theory predicts selection for the correct mode of gene control. It also makes surprising predictions concerning the organism's phenotype and habitat.
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UR - http://www.scopus.com/inward/citedby.url?scp=18544396174&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:18544396174
VL - 28
JO - Annals of Biomedical Engineering
JF - Annals of Biomedical Engineering
SN - 0090-6964
IS - SUPPL. 1
ER -