Function, design and evolution of elementary gene circuits

Michael Savageau

Research output: Contribution to journalArticle

Abstract

This report describes recent work on a quantitative theory that relates molecular mechanisms of gene control to the organism's physiological behavior in its natural environment. When applied to catabolic operons of Escherichia coli in the human intestine, the theory predicts selection for the correct mode of gene control. It also makes surprising predictions concerning the organism's phenotype and habitat.

Original languageEnglish (US)
JournalAnnals of Biomedical Engineering
Volume28
Issue numberSUPPL. 1
StatePublished - 2000
Externally publishedYes

ASJC Scopus subject areas

  • Biomedical Engineering

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