Fulminant demyelinating neuropathy mimicking cerebral death

Nandini Bakshi, Ricardo A Maselli, Sidney M. Gospe, William G. Ellis, Craig M McDonald, Raul N. Mandler

Research output: Contribution to journalArticlepeer-review

58 Scopus citations


Guillain-Barre syndrome can very rarely present with acute quadripares and cranial nerve involvement resembling a locked-in state. We describe a very unusual case of fulminant neuropathy in a child who was previously exposed to vincristine. The clinical picture resembled brain death; however, electrodiagnostic studies led to the diagnosis of a peripheral neuropathy. Serial electrodiagnostic studies and pathologic findings confirmed demyelination.

Original languageEnglish (US)
Pages (from-to)1595-1597
Number of pages3
JournalMuscle and Nerve
Issue number12
StatePublished - 1997


  • Brain death
  • Guillain-Barre syndrome
  • Inexcitable nerves
  • Peripheral neuropathy
  • Vincristine neuropathy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


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