From neutrophil rolling to arrest: Topographic requirements of signaling via L-selectin

Scott I. Simon, David Pearson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The topographic requirements of signaling via L-selectin were discussed. It was found that signaling was regulated by the ligand affinity, valency of binding and by the extent of receptor clustering. The binding events and receptor recognition that lead to the activation were also discussed.

Original languageEnglish (US)
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
EditorsR.D. Kamm, G.W. Schmid-Schoenbein, G.A. Atesian, M.S. Hefzy
Pages663-664
Number of pages2
Volume50
StatePublished - 2001
EventProceedings of the 2001 Bioengineering Conference - Snowbird, UT, United States
Duration: Jun 27 2001Jul 1 2001

Other

OtherProceedings of the 2001 Bioengineering Conference
CountryUnited States
CitySnowbird, UT
Period6/27/017/1/01

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Simon, S. I., & Pearson, D. (2001). From neutrophil rolling to arrest: Topographic requirements of signaling via L-selectin. In R. D. Kamm, G. W. Schmid-Schoenbein, G. A. Atesian, & M. S. Hefzy (Eds.), American Society of Mechanical Engineers, Bioengineering Division (Publication) BED (Vol. 50, pp. 663-664)