Frictionless sliding of single-stranded DNA in a carbon nanotube pore observed by single molecule force spectroscopy

Valentin Lulevich, Sangil Kim, Costas P. Grigoropoulos, Aleksandr Noy

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Smooth inner pores of carbon nanotubes (CNT) provide a fascinating model for studying biological transport. We used an atomic force microscope to pull a single-stranded DNA oligomer from a carbon nanotube pore. DNA extraction from CNT pores occurs at a nearly constant force, which is drastically different from the elastic profile commonly observed during polymer stretching with atomic force microscopy. We show that a combination of the frictionless nanotube pore walls and an unfavorable DNA solvation energy produces this constant force profiles.

Original languageEnglish (US)
Pages (from-to)1171-1176
Number of pages6
JournalNano Letters
Volume11
Issue number3
DOIs
StatePublished - Mar 9 2011
Externally publishedYes

Fingerprint

Carbon Nanotubes
Single-Stranded DNA
sliding
Carbon nanotubes
DNA
deoxyribonucleic acid
carbon nanotubes
Spectroscopy
porosity
Molecules
spectroscopy
molecules
Solvation
Oligomers
Nanotubes
Stretching
Atomic force microscopy
Polymers
Microscopes
profiles

Keywords

  • carbon nanotubes
  • CNT membrane
  • DNA
  • molecular friction
  • nanofluidics
  • Single molecule force spectroscopy

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Mechanical Engineering

Cite this

Frictionless sliding of single-stranded DNA in a carbon nanotube pore observed by single molecule force spectroscopy. / Lulevich, Valentin; Kim, Sangil; Grigoropoulos, Costas P.; Noy, Aleksandr.

In: Nano Letters, Vol. 11, No. 3, 09.03.2011, p. 1171-1176.

Research output: Contribution to journalArticle

Lulevich, Valentin ; Kim, Sangil ; Grigoropoulos, Costas P. ; Noy, Aleksandr. / Frictionless sliding of single-stranded DNA in a carbon nanotube pore observed by single molecule force spectroscopy. In: Nano Letters. 2011 ; Vol. 11, No. 3. pp. 1171-1176.
@article{158900903f3147e68d8d138eda910d45,
title = "Frictionless sliding of single-stranded DNA in a carbon nanotube pore observed by single molecule force spectroscopy",
abstract = "Smooth inner pores of carbon nanotubes (CNT) provide a fascinating model for studying biological transport. We used an atomic force microscope to pull a single-stranded DNA oligomer from a carbon nanotube pore. DNA extraction from CNT pores occurs at a nearly constant force, which is drastically different from the elastic profile commonly observed during polymer stretching with atomic force microscopy. We show that a combination of the frictionless nanotube pore walls and an unfavorable DNA solvation energy produces this constant force profiles.",
keywords = "carbon nanotubes, CNT membrane, DNA, molecular friction, nanofluidics, Single molecule force spectroscopy",
author = "Valentin Lulevich and Sangil Kim and Grigoropoulos, {Costas P.} and Aleksandr Noy",
year = "2011",
month = "3",
day = "9",
doi = "10.1021/nl104116s",
language = "English (US)",
volume = "11",
pages = "1171--1176",
journal = "Nano Letters",
issn = "1530-6984",
publisher = "American Chemical Society",
number = "3",

}

TY - JOUR

T1 - Frictionless sliding of single-stranded DNA in a carbon nanotube pore observed by single molecule force spectroscopy

AU - Lulevich, Valentin

AU - Kim, Sangil

AU - Grigoropoulos, Costas P.

AU - Noy, Aleksandr

PY - 2011/3/9

Y1 - 2011/3/9

N2 - Smooth inner pores of carbon nanotubes (CNT) provide a fascinating model for studying biological transport. We used an atomic force microscope to pull a single-stranded DNA oligomer from a carbon nanotube pore. DNA extraction from CNT pores occurs at a nearly constant force, which is drastically different from the elastic profile commonly observed during polymer stretching with atomic force microscopy. We show that a combination of the frictionless nanotube pore walls and an unfavorable DNA solvation energy produces this constant force profiles.

AB - Smooth inner pores of carbon nanotubes (CNT) provide a fascinating model for studying biological transport. We used an atomic force microscope to pull a single-stranded DNA oligomer from a carbon nanotube pore. DNA extraction from CNT pores occurs at a nearly constant force, which is drastically different from the elastic profile commonly observed during polymer stretching with atomic force microscopy. We show that a combination of the frictionless nanotube pore walls and an unfavorable DNA solvation energy produces this constant force profiles.

KW - carbon nanotubes

KW - CNT membrane

KW - DNA

KW - molecular friction

KW - nanofluidics

KW - Single molecule force spectroscopy

UR - http://www.scopus.com/inward/record.url?scp=79952606033&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79952606033&partnerID=8YFLogxK

U2 - 10.1021/nl104116s

DO - 10.1021/nl104116s

M3 - Article

C2 - 21275410

AN - SCOPUS:79952606033

VL - 11

SP - 1171

EP - 1176

JO - Nano Letters

JF - Nano Letters

SN - 1530-6984

IS - 3

ER -