Frequency of detectable serum IgG concentrations in precolostral calves

Munashe Chigerwe, Jeff W. Tyler, Dusty W. Nagy, John R. Middleton

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Objective - To determine the prevalence of detectable serum IgG concentrations in calves prior to ingestion of colostrum and to assess whether a detectable IgG concentration was related to dam parity, calf birth weight, calf sex, season of calving, or infectious agents that can be transmitted transplacentally. Animals - 170 Holstein dairy calves. Procedures - Serum samples were obtained from calves prior to ingestion of colostrum, and serologic testing for bovine viral diarrhea virus (BVDV) and Neospora caninum was performed. Relative risk, attributable risk, population attributable risk, and population attributable fraction for calves with a detectable serum IgG concentration attributable to positive results for N caninum and BVDV serologic testing were calculated. Logistic regression analysis was used to determine whether dam parity, calf sex, season of calving, and calf weight were associated with precolostral IgG concentration. Results - 90 (52.9%) calves had a detectable total serum IgG concentration (IgG ≥ 16 mg/dL). Relative risk, attributable risk, population attributable risk, and population attributable fraction for calves with a detectable serum IgG concentration attributable to positive results for N caninum serologic testing were 1.66, 0.34, 0.014, and 0.03, respectively. Calf sex, calf birth weight, and season of calving were not significant predictors for detection of serum IgG in precolostral samples. Conclusions and Clinical Relevance - Prevalence of IgG concentrations in precolostral serum samples was higher than reported elsewhere. There was no apparent link between serum antibodies against common infectious agents that can be transmitted transplacentally and detection of measurable serum IgG concentrations.

Original languageEnglish (US)
Pages (from-to)791-795
Number of pages5
JournalAmerican Journal of Veterinary Research
Volume69
Issue number6
DOIs
StatePublished - Jun 2008
Externally publishedYes

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Immunoglobulin G
calves
Serum
Bovine Viral Diarrhea Viruses
Colostrum
calving
Parity
Bovine viral diarrhea virus
Birth Weight
relative risk
parity (reproduction)
Population
colostrum
birth weight
gender
Eating
Neospora
ingestion
dairy calves
pathogens

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Frequency of detectable serum IgG concentrations in precolostral calves. / Chigerwe, Munashe; Tyler, Jeff W.; Nagy, Dusty W.; Middleton, John R.

In: American Journal of Veterinary Research, Vol. 69, No. 6, 06.2008, p. 791-795.

Research output: Contribution to journalArticle

Chigerwe, Munashe ; Tyler, Jeff W. ; Nagy, Dusty W. ; Middleton, John R. / Frequency of detectable serum IgG concentrations in precolostral calves. In: American Journal of Veterinary Research. 2008 ; Vol. 69, No. 6. pp. 791-795.
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