Abstract
Objective - To determine the prevalence of detectable serum IgG concentrations in calves prior to ingestion of colostrum and to assess whether a detectable IgG concentration was related to dam parity, calf birth weight, calf sex, season of calving, or infectious agents that can be transmitted transplacentally. Animals - 170 Holstein dairy calves. Procedures - Serum samples were obtained from calves prior to ingestion of colostrum, and serologic testing for bovine viral diarrhea virus (BVDV) and Neospora caninum was performed. Relative risk, attributable risk, population attributable risk, and population attributable fraction for calves with a detectable serum IgG concentration attributable to positive results for N caninum and BVDV serologic testing were calculated. Logistic regression analysis was used to determine whether dam parity, calf sex, season of calving, and calf weight were associated with precolostral IgG concentration. Results - 90 (52.9%) calves had a detectable total serum IgG concentration (IgG ≥ 16 mg/dL). Relative risk, attributable risk, population attributable risk, and population attributable fraction for calves with a detectable serum IgG concentration attributable to positive results for N caninum serologic testing were 1.66, 0.34, 0.014, and 0.03, respectively. Calf sex, calf birth weight, and season of calving were not significant predictors for detection of serum IgG in precolostral samples. Conclusions and Clinical Relevance - Prevalence of IgG concentrations in precolostral serum samples was higher than reported elsewhere. There was no apparent link between serum antibodies against common infectious agents that can be transmitted transplacentally and detection of measurable serum IgG concentrations.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 791-795 |
| Number of pages | 5 |
| Journal | American Journal of Veterinary Research |
| Volume | 69 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 2008 |
| Externally published | Yes |
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ASJC Scopus subject areas
- veterinary(all)
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Frequency of detectable serum IgG concentrations in precolostral calves. / Chigerwe, Munashe; Tyler, Jeff W.; Nagy, Dusty W.; Middleton, John R.
In: American Journal of Veterinary Research, Vol. 69, No. 6, 06.2008, p. 791-795.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Frequency of detectable serum IgG concentrations in precolostral calves
AU - Chigerwe, Munashe
AU - Tyler, Jeff W.
AU - Nagy, Dusty W.
AU - Middleton, John R.
PY - 2008/6
Y1 - 2008/6
N2 - Objective - To determine the prevalence of detectable serum IgG concentrations in calves prior to ingestion of colostrum and to assess whether a detectable IgG concentration was related to dam parity, calf birth weight, calf sex, season of calving, or infectious agents that can be transmitted transplacentally. Animals - 170 Holstein dairy calves. Procedures - Serum samples were obtained from calves prior to ingestion of colostrum, and serologic testing for bovine viral diarrhea virus (BVDV) and Neospora caninum was performed. Relative risk, attributable risk, population attributable risk, and population attributable fraction for calves with a detectable serum IgG concentration attributable to positive results for N caninum and BVDV serologic testing were calculated. Logistic regression analysis was used to determine whether dam parity, calf sex, season of calving, and calf weight were associated with precolostral IgG concentration. Results - 90 (52.9%) calves had a detectable total serum IgG concentration (IgG ≥ 16 mg/dL). Relative risk, attributable risk, population attributable risk, and population attributable fraction for calves with a detectable serum IgG concentration attributable to positive results for N caninum serologic testing were 1.66, 0.34, 0.014, and 0.03, respectively. Calf sex, calf birth weight, and season of calving were not significant predictors for detection of serum IgG in precolostral samples. Conclusions and Clinical Relevance - Prevalence of IgG concentrations in precolostral serum samples was higher than reported elsewhere. There was no apparent link between serum antibodies against common infectious agents that can be transmitted transplacentally and detection of measurable serum IgG concentrations.
AB - Objective - To determine the prevalence of detectable serum IgG concentrations in calves prior to ingestion of colostrum and to assess whether a detectable IgG concentration was related to dam parity, calf birth weight, calf sex, season of calving, or infectious agents that can be transmitted transplacentally. Animals - 170 Holstein dairy calves. Procedures - Serum samples were obtained from calves prior to ingestion of colostrum, and serologic testing for bovine viral diarrhea virus (BVDV) and Neospora caninum was performed. Relative risk, attributable risk, population attributable risk, and population attributable fraction for calves with a detectable serum IgG concentration attributable to positive results for N caninum and BVDV serologic testing were calculated. Logistic regression analysis was used to determine whether dam parity, calf sex, season of calving, and calf weight were associated with precolostral IgG concentration. Results - 90 (52.9%) calves had a detectable total serum IgG concentration (IgG ≥ 16 mg/dL). Relative risk, attributable risk, population attributable risk, and population attributable fraction for calves with a detectable serum IgG concentration attributable to positive results for N caninum serologic testing were 1.66, 0.34, 0.014, and 0.03, respectively. Calf sex, calf birth weight, and season of calving were not significant predictors for detection of serum IgG in precolostral samples. Conclusions and Clinical Relevance - Prevalence of IgG concentrations in precolostral serum samples was higher than reported elsewhere. There was no apparent link between serum antibodies against common infectious agents that can be transmitted transplacentally and detection of measurable serum IgG concentrations.
UR - http://www.scopus.com/inward/record.url?scp=45949105874&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=45949105874&partnerID=8YFLogxK
U2 - 10.2460/ajvr.69.6.791
DO - 10.2460/ajvr.69.6.791
M3 - Article
C2 - 18518660
AN - SCOPUS:45949105874
VL - 69
SP - 791
EP - 795
JO - American Journal of Veterinary Research
JF - American Journal of Veterinary Research
SN - 0002-9645
IS - 6
ER -