TY - JOUR
T1 - Fragile X syndrome
T2 - an overview of cause, characteristics, assessment and management
AU - Crawford, Hayley
AU - Abbeduto, Leonard
AU - Hall, Scott S.
AU - Hardiman, Rebecca
AU - Hessl, David
AU - Roberts, Jane E.
AU - Scerif, Gaia
AU - Stanfield, Andrew C.
AU - Turk, Jeremy
AU - Oliver, Chris
N1 - Publisher Copyright:
© 2020
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/11
Y1 - 2020/11
N2 - Fragile X syndrome (FXS) is the most common identifiable cause of inherited intellectual disability and autism spectrum conditions, and is associated with a range of physical, cognitive and behavioural characteristics. Alongside intellectual disability, heightened rates of autism spectrum disorder, anxiety disorders, attention-deficit-hyperactivity disorder, self-injury and aggression are reported. Timely identification of FXS as well as assessments of common co-morbid psychological conditions and underlying health problems are essential to ensure individuals with FXS receive appropriate support. This article provides an overview for clinicians of current literature on the cause of FXS as well as the key physical, cognitive, and behavioural characteristics with a focus on children and adolescents.
AB - Fragile X syndrome (FXS) is the most common identifiable cause of inherited intellectual disability and autism spectrum conditions, and is associated with a range of physical, cognitive and behavioural characteristics. Alongside intellectual disability, heightened rates of autism spectrum disorder, anxiety disorders, attention-deficit-hyperactivity disorder, self-injury and aggression are reported. Timely identification of FXS as well as assessments of common co-morbid psychological conditions and underlying health problems are essential to ensure individuals with FXS receive appropriate support. This article provides an overview for clinicians of current literature on the cause of FXS as well as the key physical, cognitive, and behavioural characteristics with a focus on children and adolescents.
KW - anxiety
KW - attention-deficit-hyperactivity-disorder
KW - autism spectrum disorder
KW - fragile X syndrome
KW - intellectual disability
UR - http://www.scopus.com/inward/record.url?scp=85090126525&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85090126525&partnerID=8YFLogxK
U2 - 10.1016/j.paed.2020.08.007
DO - 10.1016/j.paed.2020.08.007
M3 - Review article
AN - SCOPUS:85090126525
VL - 30
SP - 400
EP - 403
JO - Paediatrics and Child Health (United Kingdom)
JF - Paediatrics and Child Health (United Kingdom)
SN - 1751-7222
IS - 11
ER -