Fragile X syndrome: An aging perspective

Andrea Schneider; Andrew Ligsay; Randi J Hagerman

doi:10.1002/ddrr.1129

Fragile X syndrome: An aging perspective

Andrea Schneider, Andrew Ligsay, Randi J Hagerman

Developmental - Behavioral Pediatrics

Research output: Contribution to journal › Article

12 Scopus citations

Abstract

Cognitive and behavioral correlates of molecular variations related to the FMR1 gene have been studied rather extensively, but research about the long-term outcome in individuals with fragile X spectrum disorders remains sparse. In this review, we present an overview of aging research and recent findings in regard to cellular and clinical manifestations of aging in fragile X syndrome, and the FMR1 premutation.

Original language	English (US)
Pages (from-to)	68-74
Number of pages	7
Journal	Developmental Disabilities Research Reviews
Volume	18
Issue number	1
DOIs	https://doi.org/10.1002/ddrr.1129
State	Published - 2013

Fingerprint

Keywords

Aging
FMRP
Fragile X syndrome
Neurodegeneration

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Psychiatry and Mental health
Developmental and Educational Psychology

Cite this

Schneider, A., Ligsay, A., & Hagerman, R. J. (2013). Fragile X syndrome: An aging perspective. Developmental Disabilities Research Reviews, 18(1), 68-74. https://doi.org/10.1002/ddrr.1129

@article{db0a76653e8b45e5adced82aa78c8ab6,

title = "Fragile X syndrome: An aging perspective",

abstract = "Cognitive and behavioral correlates of molecular variations related to the FMR1 gene have been studied rather extensively, but research about the long-term outcome in individuals with fragile X spectrum disorders remains sparse. In this review, we present an overview of aging research and recent findings in regard to cellular and clinical manifestations of aging in fragile X syndrome, and the FMR1 premutation.",

keywords = "Aging, FMRP, Fragile X syndrome, Neurodegeneration",

author = "Andrea Schneider and Andrew Ligsay and Hagerman, {Randi J}",

year = "2013",

doi = "10.1002/ddrr.1129",

language = "English (US)",

volume = "18",

pages = "68--74",

journal = "Developmental Disabilities Research Reviews",

issn = "1940-5510",

publisher = "Wiley-Blackwell",

number = "1",

}

TY - JOUR

T1 - Fragile X syndrome

T2 - An aging perspective

AU - Schneider, Andrea

AU - Ligsay, Andrew

AU - Hagerman, Randi J

PY - 2013

Y1 - 2013

N2 - Cognitive and behavioral correlates of molecular variations related to the FMR1 gene have been studied rather extensively, but research about the long-term outcome in individuals with fragile X spectrum disorders remains sparse. In this review, we present an overview of aging research and recent findings in regard to cellular and clinical manifestations of aging in fragile X syndrome, and the FMR1 premutation.

AB - Cognitive and behavioral correlates of molecular variations related to the FMR1 gene have been studied rather extensively, but research about the long-term outcome in individuals with fragile X spectrum disorders remains sparse. In this review, we present an overview of aging research and recent findings in regard to cellular and clinical manifestations of aging in fragile X syndrome, and the FMR1 premutation.

KW - Aging

KW - FMRP

KW - Fragile X syndrome

KW - Neurodegeneration

UR - http://www.scopus.com/inward/record.url?scp=84893491304&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84893491304&partnerID=8YFLogxK

U2 - 10.1002/ddrr.1129

DO - 10.1002/ddrr.1129

M3 - Article

C2 - 23949830

AN - SCOPUS:84893491304

VL - 18

SP - 68

EP - 74

JO - Developmental Disabilities Research Reviews

JF - Developmental Disabilities Research Reviews

SN - 1940-5510

IS - 1

ER -

Access to Document

10.1002/ddrr.1129