Fragile X syndrome: An aging perspective

Andrea Schneider; Andrew Ligsay; Randi J Hagerman

doi:10.1002/ddrr.1129

Fragile X syndrome: An aging perspective

Andrea Schneider, Andrew Ligsay, Randi J Hagerman

Developmental - Behavioral Pediatrics

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Cognitive and behavioral correlates of molecular variations related to the FMR1 gene have been studied rather extensively, but research about the long-term outcome in individuals with fragile X spectrum disorders remains sparse. In this review, we present an overview of aging research and recent findings in regard to cellular and clinical manifestations of aging in fragile X syndrome, and the FMR1 premutation.

Original language	English (US)
Pages (from-to)	68-74
Number of pages	7
Journal	Developmental Disabilities Research Reviews
Volume	18
Issue number	1
DOIs	https://doi.org/10.1002/ddrr.1129
State	Published - 2013

Keywords

Aging
FMRP
Fragile X syndrome
Neurodegeneration

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Psychiatry and Mental health
Developmental and Educational Psychology

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10.1002/ddrr.1129

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abstract = "Cognitive and behavioral correlates of molecular variations related to the FMR1 gene have been studied rather extensively, but research about the long-term outcome in individuals with fragile X spectrum disorders remains sparse. In this review, we present an overview of aging research and recent findings in regard to cellular and clinical manifestations of aging in fragile X syndrome, and the FMR1 premutation.",

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AU - Ligsay, Andrew

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AB - Cognitive and behavioral correlates of molecular variations related to the FMR1 gene have been studied rather extensively, but research about the long-term outcome in individuals with fragile X spectrum disorders remains sparse. In this review, we present an overview of aging research and recent findings in regard to cellular and clinical manifestations of aging in fragile X syndrome, and the FMR1 premutation.

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KW - FMRP

KW - Fragile X syndrome

KW - Neurodegeneration

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Fragile X syndrome: An aging perspective

Abstract

Keywords

ASJC Scopus subject areas

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