Fragile X syndrome: An aging perspective

Andrea Schneider, Andrew Ligsay, Randi J Hagerman

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Cognitive and behavioral correlates of molecular variations related to the FMR1 gene have been studied rather extensively, but research about the long-term outcome in individuals with fragile X spectrum disorders remains sparse. In this review, we present an overview of aging research and recent findings in regard to cellular and clinical manifestations of aging in fragile X syndrome, and the FMR1 premutation.

Original languageEnglish (US)
Pages (from-to)68-74
Number of pages7
JournalDevelopmental Disabilities Research Reviews
Volume18
Issue number1
DOIs
StatePublished - 2013

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Keywords

  • Aging
  • FMRP
  • Fragile X syndrome
  • Neurodegeneration

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Psychiatry and Mental health
  • Developmental and Educational Psychology

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