Fragile X syndrome

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

Fragile X syndrome (FXS) is the most common inherited cause of mental retardation known and has a strong association with autism. Approximately 2-6 percent of males with autism have FXS, and 15-33 percent of children with FXS have autism (Bailey et al., 2001b; Rogers et al., 2001; Hagerman, 2002). FXS represents a distinct subgroup of autism, and the study of the behavioral phenotype, neurobiology, and molecular genetics of FXS could lead to new insights regarding pathophysiology that may be applicable to other causes of autism. FXS is a model of how a single-gene disorder can affect the expression of multiple genes that may be held in common with other etiologies of autism.

Original languageEnglish (US)
Title of host publicationThe Neurobiology of Autism
PublisherThe Johns Hopkins University Press
Pages251-264
Number of pages14
ISBN (Print)9780801880476
StatePublished - 2005

ASJC Scopus subject areas

  • Social Sciences(all)

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    Hagerman, R. J. (2005). Fragile X syndrome. In The Neurobiology of Autism (pp. 251-264). The Johns Hopkins University Press.