Focal posterior interosseous neuropathy in the presence of hereditary motor and sensory neuropathy, type I

Gregory T. Carter, David D. Kilmer, Robert M Szabo, Craig M McDonald

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

A 30-year-old male with hereditary motor and sensory neuropathy, type I (HMSN I), presented with asymmetric weakness of finger extension and radial deviation with left wrist extension, previously felt to be a manifestation of the peripheral neuropathy. Nerve conduction studies confirmed HMSN I; however, needle EMG revealed marked, ongoing axonal loss in muscles innervated by the left posterior interosseous nerve (PIN) only. At surgery there was focal fusiform swelling in the PIN at exit from the supinator muscle, compatible with localized hypertrophic neuropathy, which has not been reported before in HMSN I. A concomitant focal mononeuropathy should be considered in cases of hereditary neuropathy with marked asymmetry of weakness.

Original languageEnglish (US)
Pages (from-to)644-648
Number of pages5
JournalMuscle and Nerve
Volume19
Issue number5
DOIs
StatePublished - May 1996
Externally publishedYes

Keywords

  • Charcot-Marie-Tooth
  • hypertrophic neuropathy
  • mononeuropathy
  • neuromuscular disease
  • perineurioma

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

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