TY - JOUR
T1 - Fluoride excess in coccidioidomycosis patients receiving long-term antifungal therapy
T2 - An assessment of currently available triazoles
AU - Thompson, George Richard
AU - Bays, Derek
AU - Cohen, Stuart H
AU - Pappagianis, Demosthenes
PY - 2012/1
Y1 - 2012/1
N2 - The use of voriconazole, a trifluorinated antifungal, has been associated with the development of fluoride excess and periostitis/ exostoses. We evaluated a cohort of patients on long-term triazole therapy and found that other fluorinated triazoles (fluconazole and posaconazole) conferred no risk for the development of hyperfluorosis and its complications in our cohort.
AB - The use of voriconazole, a trifluorinated antifungal, has been associated with the development of fluoride excess and periostitis/ exostoses. We evaluated a cohort of patients on long-term triazole therapy and found that other fluorinated triazoles (fluconazole and posaconazole) conferred no risk for the development of hyperfluorosis and its complications in our cohort.
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U2 - 10.1128/AAC.05275-11
DO - 10.1128/AAC.05275-11
M3 - Article
C2 - 22005993
AN - SCOPUS:84455192484
VL - 56
SP - 563
EP - 564
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 1
ER -