Fluorescence lifetime spectroscopy and imaging techniques in medical applications

Dimitris Gorpas; Laura Marcu

doi:10.1007/978-981-287-627-0_1

Fluorescence lifetime spectroscopy and imaging techniques in medical applications

Dimitris Gorpas, Laura Marcu

Neurological Surgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Scopus citations

Abstract

This chapter reviews the fluorescence lifetime techniques currently applied in biomedical diagnostics. Specifically the chapter focuses on time-resolved fluorescence spectroscopy (TRFS) and fluorescence lifetime imaging (FLIM) technologies for in vivo tissue characterization, with special emphasis on the translational potential of these techniques and the prospects of autofluorescence to provide intrinsic contrast for the assessment and diagnosis of human diseases. The use of these techniques in a number of medical applications, including cancer (gastrointestinal tract, lung, head and neck, brain and breast), skin and eye diseases, and atherosclerotic cardiovascular disease, are discussed and their recent developments towards translational medicine are highlighted.

Original language	English (US)
Title of host publication	Frontiers in Biophotonics for Translational Medicine: In the Celebration of Year of Light (2015)
Publisher	Springer Singapore
Pages	1-46
Number of pages	46
ISBN (Electronic)	9789812876270
ISBN (Print)	9789812876263
DOIs	https://doi.org/10.1007/978-981-287-627-0_1
State	Published - Jul 3 2015

ASJC Scopus subject areas

Engineering(all)
Biochemistry, Genetics and Molecular Biology(all)
Materials Science(all)
Physics and Astronomy(all)

Access to Document

10.1007/978-981-287-627-0_1

Fingerprint Dive into the research topics of 'Fluorescence lifetime spectroscopy and imaging techniques in medical applications'. Together they form a unique fingerprint.

Cite this

@inbook{d7f8db99d99741c180d1ede67b528010,

title = "Fluorescence lifetime spectroscopy and imaging techniques in medical applications",

abstract = "This chapter reviews the fluorescence lifetime techniques currently applied in biomedical diagnostics. Specifically the chapter focuses on time-resolved fluorescence spectroscopy (TRFS) and fluorescence lifetime imaging (FLIM) technologies for in vivo tissue characterization, with special emphasis on the translational potential of these techniques and the prospects of autofluorescence to provide intrinsic contrast for the assessment and diagnosis of human diseases. The use of these techniques in a number of medical applications, including cancer (gastrointestinal tract, lung, head and neck, brain and breast), skin and eye diseases, and atherosclerotic cardiovascular disease, are discussed and their recent developments towards translational medicine are highlighted.",

author = "Dimitris Gorpas and Laura Marcu",

year = "2015",

month = jul,

day = "3",

doi = "10.1007/978-981-287-627-0_1",

language = "English (US)",

isbn = "9789812876263",

pages = "1--46",

booktitle = "Frontiers in Biophotonics for Translational Medicine: In the Celebration of Year of Light (2015)",

publisher = "Springer Singapore",

}

TY - CHAP

T1 - Fluorescence lifetime spectroscopy and imaging techniques in medical applications

AU - Gorpas, Dimitris

AU - Marcu, Laura

PY - 2015/7/3

Y1 - 2015/7/3

N2 - This chapter reviews the fluorescence lifetime techniques currently applied in biomedical diagnostics. Specifically the chapter focuses on time-resolved fluorescence spectroscopy (TRFS) and fluorescence lifetime imaging (FLIM) technologies for in vivo tissue characterization, with special emphasis on the translational potential of these techniques and the prospects of autofluorescence to provide intrinsic contrast for the assessment and diagnosis of human diseases. The use of these techniques in a number of medical applications, including cancer (gastrointestinal tract, lung, head and neck, brain and breast), skin and eye diseases, and atherosclerotic cardiovascular disease, are discussed and their recent developments towards translational medicine are highlighted.

AB - This chapter reviews the fluorescence lifetime techniques currently applied in biomedical diagnostics. Specifically the chapter focuses on time-resolved fluorescence spectroscopy (TRFS) and fluorescence lifetime imaging (FLIM) technologies for in vivo tissue characterization, with special emphasis on the translational potential of these techniques and the prospects of autofluorescence to provide intrinsic contrast for the assessment and diagnosis of human diseases. The use of these techniques in a number of medical applications, including cancer (gastrointestinal tract, lung, head and neck, brain and breast), skin and eye diseases, and atherosclerotic cardiovascular disease, are discussed and their recent developments towards translational medicine are highlighted.

UR - http://www.scopus.com/inward/record.url?scp=84957353309&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84957353309&partnerID=8YFLogxK

U2 - 10.1007/978-981-287-627-0_1

DO - 10.1007/978-981-287-627-0_1

M3 - Chapter

AN - SCOPUS:84957353309

SN - 9789812876263

SP - 1

EP - 46

BT - Frontiers in Biophotonics for Translational Medicine: In the Celebration of Year of Light (2015)

PB - Springer Singapore

ER -