Fluorescence lifetime spectroscopy and imaging techniques in medical applications

Dimitris Gorpas; Laura Marcu

doi:10.1007/978-981-287-627-0_1

Fluorescence lifetime spectroscopy and imaging techniques in medical applications

Dimitris Gorpas, Laura Marcu

Neurological Surgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Scopus citations

Abstract

This chapter reviews the fluorescence lifetime techniques currently applied in biomedical diagnostics. Specifically the chapter focuses on time-resolved fluorescence spectroscopy (TRFS) and fluorescence lifetime imaging (FLIM) technologies for in vivo tissue characterization, with special emphasis on the translational potential of these techniques and the prospects of autofluorescence to provide intrinsic contrast for the assessment and diagnosis of human diseases. The use of these techniques in a number of medical applications, including cancer (gastrointestinal tract, lung, head and neck, brain and breast), skin and eye diseases, and atherosclerotic cardiovascular disease, are discussed and their recent developments towards translational medicine are highlighted.

Original language	English (US)
Title of host publication	Frontiers in Biophotonics for Translational Medicine: In the Celebration of Year of Light (2015)
Publisher	Springer Singapore
Pages	1-46
Number of pages	46
ISBN (Electronic)	9789812876270
ISBN (Print)	9789812876263
DOIs	https://doi.org/10.1007/978-981-287-627-0_1
State	Published - Jul 3 2015

ASJC Scopus subject areas

Engineering(all)
Biochemistry, Genetics and Molecular Biology(all)
Materials Science(all)
Physics and Astronomy(all)

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Gorpas, D., & Marcu, L. (2015). Fluorescence lifetime spectroscopy and imaging techniques in medical applications. In Frontiers in Biophotonics for Translational Medicine: In the Celebration of Year of Light (2015) (pp. 1-46). Springer Singapore. https://doi.org/10.1007/978-981-287-627-0_1

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