Fluorescence lifetime imaging microscopy (FLIM) for intraoperative tumor delineation: A study in patients

Yinghua Sun, Jeremy Meier, Nisa Hatami, Jennifer Phipps, Rudolph J. Schrot, Brian Poirier, D Gregory Farwell, Daniel S. Elson, Laura Marcu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This communication demonstrates a novel application of an endoscopic fluorescence lifetime imaging microscopy (FLIM) system to the intraoperative diagnosis of the brain tumor glioblastoma multiforme (GBM) and head and neck tumor squamous cell carcinoma (SCC) in human patients. Current results show the potential of FLIM for delineation of both tumor types from surrounding normal tissue in surgical setting.

Original languageEnglish (US)
Title of host publicationOptics InfoBase Conference Papers
StatePublished - 2011
EventBio-Optics: Design and Application, BODA 2011 - Monterey, CA, United States
Duration: Apr 4 2011Apr 6 2011

Other

OtherBio-Optics: Design and Application, BODA 2011
CountryUnited States
CityMonterey, CA
Period4/4/114/6/11

Fingerprint

delineation
Tumors
Microscopic examination
tumors
Fluorescence
microscopy
Imaging techniques
life (durability)
fluorescence
brain
Brain
cancer
communication
Tissue
Communication

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

Cite this

Sun, Y., Meier, J., Hatami, N., Phipps, J., Schrot, R. J., Poirier, B., ... Marcu, L. (2011). Fluorescence lifetime imaging microscopy (FLIM) for intraoperative tumor delineation: A study in patients. In Optics InfoBase Conference Papers

Fluorescence lifetime imaging microscopy (FLIM) for intraoperative tumor delineation : A study in patients. / Sun, Yinghua; Meier, Jeremy; Hatami, Nisa; Phipps, Jennifer; Schrot, Rudolph J.; Poirier, Brian; Farwell, D Gregory; Elson, Daniel S.; Marcu, Laura.

Optics InfoBase Conference Papers. 2011.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Sun, Y, Meier, J, Hatami, N, Phipps, J, Schrot, RJ, Poirier, B, Farwell, DG, Elson, DS & Marcu, L 2011, Fluorescence lifetime imaging microscopy (FLIM) for intraoperative tumor delineation: A study in patients. in Optics InfoBase Conference Papers. Bio-Optics: Design and Application, BODA 2011, Monterey, CA, United States, 4/4/11.
Sun Y, Meier J, Hatami N, Phipps J, Schrot RJ, Poirier B et al. Fluorescence lifetime imaging microscopy (FLIM) for intraoperative tumor delineation: A study in patients. In Optics InfoBase Conference Papers. 2011
Sun, Yinghua ; Meier, Jeremy ; Hatami, Nisa ; Phipps, Jennifer ; Schrot, Rudolph J. ; Poirier, Brian ; Farwell, D Gregory ; Elson, Daniel S. ; Marcu, Laura. / Fluorescence lifetime imaging microscopy (FLIM) for intraoperative tumor delineation : A study in patients. Optics InfoBase Conference Papers. 2011.
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