Fluorescence lifetime imaging distinguishes glioblastoma multiforme infiltrative edges in patients

Silvia Noble Anbunesan, Alba Alfonso-Garcia, Brent W. Weyers, Julien Bec, Roberto P. Frusciante, Matthew Bobinski, Han Sung Lee, Orin Bloch, Laura Marcu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Fluorescence lifetime imaging was used during open craniotomy procedures to detect differences between healthy and tumor-infiltrated brain. Optical parameters validated against histopathological biomarkers demonstrate that brain regions with infiltrative glioblastoma multiforme are characterized by longer lifetime values relative to the adjacent healthy tissues.

Original languageEnglish (US)
Title of host publicationBio-Optics
Subtitle of host publicationDesign and Application, BODA 2021
PublisherThe Optical Society
ISBN (Electronic)9781557528209
StatePublished - 2021
EventBio-Optics: Design and Application, BODA 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021 - Virtual, Online, United States
Duration: Apr 12 2021Apr 16 2021

Publication series

NameOptics InfoBase Conference Papers

Conference

ConferenceBio-Optics: Design and Application, BODA 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021
Country/TerritoryUnited States
CityVirtual, Online
Period4/12/214/16/21

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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