Fluorescence lifetime imaging applications in tissue engineering

Bernard Y. Binder, Jonathan K Leach, Laura Marcu

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The field of tissue engineering has emerged from the related areas of cellular/molecular biology and engineering as a unique discipline focused on the development and implementation of functional biological replacements for tissues and organs (Langer and Vacanti 1993). The successful creation of tissues that can effectively serve as physiological replacements or accurate biological models of development and pathology requires the appropriate combination of numerous variables including cellular populations, an underlying matrix, and soluble signals. Due to the complexity and dynamic nature of biological systems, establishing a firm understanding of the intracellular and intercellular processes in target tissues is paramount for successful advances in tissue engineering and regenerative medicine (Georgakoudi et al. 2008).

Original languageEnglish (US)
Title of host publicationFluorescence Lifetime Spectroscopy and Imaging
Subtitle of host publicationPrinciples and Applications in Biomedical Diagnostics
PublisherCRC Press
Pages449-458
Number of pages10
ISBN (Electronic)9781439861684
ISBN (Print)9781439861677
DOIs
StatePublished - Jan 1 2014

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Binder, B. Y., Leach, J. K., & Marcu, L. (2014). Fluorescence lifetime imaging applications in tissue engineering. In Fluorescence Lifetime Spectroscopy and Imaging: Principles and Applications in Biomedical Diagnostics (pp. 449-458). CRC Press. https://doi.org/10.1201/b17018