FLUID WAVES IN RENAL TUBULES.

D. J. Marsh, A. S. Wexler, T. Sakai, D. A. Craig

Research output: Contribution to journalArticle

Abstract

Autoregulation of renal blood flow is ineffective when arterial pressure perturbations occur at frequencies above . 05 Hz. To determine whether wave propagation velocity to the macula densa is rate limiting, we estimated compliances of the proximal tubule and the loop of Henle, and used these values in a model of pressure and flow as functions of time and distance in the nephron. Compliances were estimated from measurements of pressures and flows in early proximal, late proximal, and early distal tubules in rats under normal and Ringer-loaded conditions. A model of steady pressure and flow in a compliant, reabsorbing tubule was fitted to these results. The transient model was a set of nonlinear hyperbolic partial differential equations with split nonlinear boundary conditions, and was solved with finite difference methods.

Original languageEnglish (US)
Pages (from-to)111-112
Number of pages2
JournalAnnals of Biomedical Engineering
Volume15
Issue number1
StatePublished - 1987
Externally publishedYes

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Fluids
Finite difference method
Wave propagation
Partial differential equations
Rats
Blood
Boundary conditions
Compliance

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Marsh, D. J., Wexler, A. S., Sakai, T., & Craig, D. A. (1987). FLUID WAVES IN RENAL TUBULES. Annals of Biomedical Engineering, 15(1), 111-112.

FLUID WAVES IN RENAL TUBULES. / Marsh, D. J.; Wexler, A. S.; Sakai, T.; Craig, D. A.

In: Annals of Biomedical Engineering, Vol. 15, No. 1, 1987, p. 111-112.

Research output: Contribution to journalArticle

Marsh, DJ, Wexler, AS, Sakai, T & Craig, DA 1987, 'FLUID WAVES IN RENAL TUBULES.', Annals of Biomedical Engineering, vol. 15, no. 1, pp. 111-112.
Marsh DJ, Wexler AS, Sakai T, Craig DA. FLUID WAVES IN RENAL TUBULES. Annals of Biomedical Engineering. 1987;15(1):111-112.
Marsh, D. J. ; Wexler, A. S. ; Sakai, T. ; Craig, D. A. / FLUID WAVES IN RENAL TUBULES. In: Annals of Biomedical Engineering. 1987 ; Vol. 15, No. 1. pp. 111-112.
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