Abstract
Wearable biosensors as a user-friendly measurement platform have become a rapidly growing field of interests due to their possibility in integrating traditional medical diagnostics and healthcare management into miniature lab-on-body analytic devices. This paper demonstrates a flexible and skin-mounted band that combines superhydrophobic-superhydrophilic microarrays with nanodendritic colorimetric biosensors toward in situ sweat sampling and analysis. Particularly, on the superwettable bands, the superhydrophobic background could confine microdroplets into superhydrophilic microwells. On-body investigations further reveal that the secreted sweat is repelled by the superhydrophobic silica coating and precisely collected and sampled onto the superhydrophilic micropatterns with negligible lateral spreading, which provides an independent "vessel" toward cellphone-based sweat biodetection (pH, chloride, glucose and calcium). Such wearable, superwettable band-based biosensors with improved interface controllability could significantly enhance epidemical sweat sampling in well-defined sites, holding a great promise for facile and noninvasive biofluids analysis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 4296-4300 |
| Number of pages | 5 |
| Journal | Analytical Chemistry |
| Volume | 91 |
| Issue number | 7 |
| DOIs | |
| State | Published - Apr 2 2019 |
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ASJC Scopus subject areas
- Analytical Chemistry
Cite this
Flexible and Superwettable Bands as a Platform toward Sweat Sampling and Sensing. / He, Xuecheng; Xu, Tailin; Gu, Zhen; Gao, Wei; Xu, Li Ping; Pan, Tingrui; Zhang, Xueji.
In: Analytical Chemistry, Vol. 91, No. 7, 02.04.2019, p. 4296-4300.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Flexible and Superwettable Bands as a Platform toward Sweat Sampling and Sensing
AU - He, Xuecheng
AU - Xu, Tailin
AU - Gu, Zhen
AU - Gao, Wei
AU - Xu, Li Ping
AU - Pan, Tingrui
AU - Zhang, Xueji
PY - 2019/4/2
Y1 - 2019/4/2
N2 - Wearable biosensors as a user-friendly measurement platform have become a rapidly growing field of interests due to their possibility in integrating traditional medical diagnostics and healthcare management into miniature lab-on-body analytic devices. This paper demonstrates a flexible and skin-mounted band that combines superhydrophobic-superhydrophilic microarrays with nanodendritic colorimetric biosensors toward in situ sweat sampling and analysis. Particularly, on the superwettable bands, the superhydrophobic background could confine microdroplets into superhydrophilic microwells. On-body investigations further reveal that the secreted sweat is repelled by the superhydrophobic silica coating and precisely collected and sampled onto the superhydrophilic micropatterns with negligible lateral spreading, which provides an independent "vessel" toward cellphone-based sweat biodetection (pH, chloride, glucose and calcium). Such wearable, superwettable band-based biosensors with improved interface controllability could significantly enhance epidemical sweat sampling in well-defined sites, holding a great promise for facile and noninvasive biofluids analysis.
AB - Wearable biosensors as a user-friendly measurement platform have become a rapidly growing field of interests due to their possibility in integrating traditional medical diagnostics and healthcare management into miniature lab-on-body analytic devices. This paper demonstrates a flexible and skin-mounted band that combines superhydrophobic-superhydrophilic microarrays with nanodendritic colorimetric biosensors toward in situ sweat sampling and analysis. Particularly, on the superwettable bands, the superhydrophobic background could confine microdroplets into superhydrophilic microwells. On-body investigations further reveal that the secreted sweat is repelled by the superhydrophobic silica coating and precisely collected and sampled onto the superhydrophilic micropatterns with negligible lateral spreading, which provides an independent "vessel" toward cellphone-based sweat biodetection (pH, chloride, glucose and calcium). Such wearable, superwettable band-based biosensors with improved interface controllability could significantly enhance epidemical sweat sampling in well-defined sites, holding a great promise for facile and noninvasive biofluids analysis.
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UR - http://www.scopus.com/inward/citedby.url?scp=85063403906&partnerID=8YFLogxK
U2 - 10.1021/acs.analchem.8b05875
DO - 10.1021/acs.analchem.8b05875
M3 - Article
C2 - 30880389
AN - SCOPUS:85063403906
VL - 91
SP - 4296
EP - 4300
JO - Analytical Chemistry
JF - Analytical Chemistry
SN - 0003-2700
IS - 7
ER -