Flavor, forced choice and deprivation affect corticosterone selection by the adrenalectomized rat

Victoria K. Willer, Thomas W. Castonguay, Mary F. Dallman, Judith S. Stern

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Adrenalectomized rats were given access to corticosterone-supplemented (20 μg/ml) and-unsupplemented saline (0.9% NaCl) in two separate bottles and preferences were measured for each. Half of the rats received corticosterone in maple-flavored saline (MAPLE group), while the other half received corticosterone in anise-flavored saline (ANISE group). Each rat also received unsupplemented saline in the alternate flavor. After an initial preference test, preferences were measured again following a period of forced choice (where rats were given the supplemented saline only) and again following a period of deprivation (where rats were given the unsupplemented saline only). All three independent variables (flavor, forced-choice and deprivation) played roles in determining self-administration of corticosterone. Results from the initial preference test demonstrated that both groups preferred the maple-flavored saline whether it contained corticosterone or not. However, consumption of corticosterone-supplemented saline regardless of flavor increased following both forced-choice and deprivation suggesting that the adrenalectomized rats were controlling their corticosterone levels. Strong negative correlations were found between intake of corticosterone-supplemented saline and body weight suggesting that the adrenalectomized rat may be controlling corticosterone levels based on some correlate of body weight.

Original languageEnglish (US)
Pages (from-to)53-59
Number of pages7
JournalPhysiology and Behavior
Volume35
Issue number1
DOIs
StatePublished - 1985

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Corticosterone
Acer
Pimpinella
Body Weight
Self Administration

Keywords

  • Adrenalectomy
  • Body weight
  • Corticosterone
  • Flavor
  • Food intake

ASJC Scopus subject areas

  • Physiology (medical)
  • Behavioral Neuroscience

Cite this

Flavor, forced choice and deprivation affect corticosterone selection by the adrenalectomized rat. / Willer, Victoria K.; Castonguay, Thomas W.; Dallman, Mary F.; Stern, Judith S.

In: Physiology and Behavior, Vol. 35, No. 1, 1985, p. 53-59.

Research output: Contribution to journalArticle

Willer, Victoria K. ; Castonguay, Thomas W. ; Dallman, Mary F. ; Stern, Judith S. / Flavor, forced choice and deprivation affect corticosterone selection by the adrenalectomized rat. In: Physiology and Behavior. 1985 ; Vol. 35, No. 1. pp. 53-59.
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